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Use of 1,6-dimethyl-8-{62 -(5-bromonicotinoyloxymethyl)-10 {60 -methoxyergoline in treating cerebral and peripheral metabolic vascular disorders

Assignee: Pfizer Italia SRL
•
Filing: 1973-04-02
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Granted: 1975-04-22
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Expires: 1993-04-02
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Abstract

Abstract 1,6-DIMETHYL-8 BETA-(5-BROMONICOTINOYL-OXYMETHYL)-10 ALPHAMETHOXY-ERGOLINE, WHICH HAS BEEN GIVEN THE NAME ''''Nicergoline'''' and constitutes a new drug active on cerebral and peripheral metabolic-vascular disorders.

Inventors

  • 👤 Aldemio Temperilli

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-08 04:39
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61K31/47; A61K31/475

Claims Analysis

Total Claims: 4
Claim 1
Independent Claim 53 words
A METHOD OF INHABITING BLOOD PLATELET AGGREGATION IN THE TREATMENT OF A CEREBRAL AND PERIPHERAL METABOLIC VASCULAR DISORDER SELECTED FROM THE GROUP CONSISTING OF CEREBRAL AND PERIPHERAL ARTERIOSCLEROSIS, RAYNAUD''S DISEASE, VASCULAR CEPHALAGIA AND MIGRANIE, WHICH COMPRISES ADMINISTERING TO A HUMAN HOST AN AMOUNT OF THE COMPOUND 1,6-DIMETHYL-8-B-(5BROMO-NICOTINOYLOXYMETHYL)-10-A-METHOXYERGOLINE EFFECTIVE TO INHABIT BLOOD PLATELET AGGREGATION.
Claim 2
Independent Claim 53 words
A METHOD OF INHABITING BLOOD PLATELET AGGREGATION IN THE TREATMENT OF A CEREBRAL AND PERIPHERAL METABOLIC VASCULAR DISORDER SELECTED FROM THE GROUP CONSISTING OF CEREBRAL AND PERIPHERAL ARTERIOSCLEROSIS, RAYNAUD''S DISEASE, VASCULAR CEPHALAGIA AND MIGRANIE, WHICH COMPRISES ADMINISTERING TO A HUMAN HOST AN AMOUNT OF THE COMPOUND 1,6-DIMETHYL-8-B-(5BROMO-NICOTINOYLOXYMETHYL)-10-A-METHOXYERGOLINE EFFECTIVE TO INHABIT BLOOD PLATELET AGGREGATION.
Claim 3
Independent Claim 57 words
A method of inhibiting blood platelet aggregation in the treatment of a cerebral and peripheral metabolic vascular disorder selected from the group consisting of cerebral and peripheral arteriosclerosis, Raynaud''s disease, vascular cephalagia and migraine, which comprises administering to a human host an amount of the compound 1,6-dimethyl-8- Beta -(5-bromo-nicotinoyloxymethyl)-10- Alpha -methoxyergoline effective to inhibit blood platelet aggregation.
Claim 4
Independent Claim 57 words
A method of inhibiting blood platelet aggregation in the treatment of a cerebral and peripheral metabolic vascular disorder selected from the group consisting of cerebral and peripheral arteriosclerosis, Raynaud''s disease, vascular cephalagia and migraine, which comprises administering to a human host an amount of the compound 1,6-dimethyl-8- Beta -(5-bromo-nicotinoyloxymethyl)-10- Alpha -methoxyergoline effective to inhibit blood platelet aggregation.

References Cited (Backward Citations)

US3228943A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1978-04-21 1978-10-21 1979-04-22 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1982-04-21 1982-10-21 1983-04-22 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1986-04-21 1986-10-21 1987-04-22 $7700.00 Window Closed / Lapsed

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