Chewable tobacco substitute composition

Claim 2

A CHEWABLE "SUBSTITUTE FOR SMOKING" GUM COMPOSITION, HAVING A "HIGH PERCENTAGE" OF GUM BASE, AS SAID "HIGH PERCENTAGE" IS HEREINAFTER DEFINED, COMPRISING:

Claim 3

A CHEWING GUM BASE AND

Claim 4

A CHEWING GUM BASE AND

Claim 5

The chewing gum composition of claim 1 wherein the amount of nicotine distributed in said chewing gum base is in the range of about 1 to about 5 milligrams, such amount of nicotine approximating that available upon smoking a cigarette.

Claim 6

nicotine, substantially uniformly distributed in said chewing gum base, wherein: A. the composition is in the form of a chewable gum unit weighing in the range of about 0.5 to about 4 grams; B. the chewing gum base is present in said gum composition in a relatively high percentage, that is, an amount constituting at least about 40 percent by weight of said gum composition; C. the nicotine is present in said composition in an amount in the range of about 0.05 weight percent to about 2 weight percent based on the weight of the chewing gum base and calculated as the free base; D. the amount of nicotine distributed in said chewing gum base is in the range of about 1 to about 10 milligrams, such amount of nicotine approximating the amount available upon smoking a smoking tobacco product; E. the nicotine being present in said gum composition as a nicotine compound selected from the group consisting of a. a nicotine free base, b. a pharmacologically-acceptable salt of nicotine, and c. a nicotine-regenerative adsorbent complex comprising a compound selected from the group consisting of nicotine and a pharmacologically-acceptable salt of nicotine sorbed on a regenerative adsorbent; F. said chewing gum composition when chewed releasing nicotine in small and reduced amounts within a period of the first few minutes of chewing, and G. especially within the first ten minutes of chewing releasing the nicotine at a rate less than if the nicotine were present in an ordinary chewing gum composition, having a relatively low percentage of chewing gum base, that is, an amount constituting less than about 40 percent by weight of the gum composition.

Claim 7

nicotine, substantially uniformly distributed in said chewing gum base, wherein: A. the composition is in the form of a chewable gum unit weighing in the range of about 0.5 to about 4 grams; B. the chewing gum base is present in said gum composition in a relatively high percentage, that is, an amount constituting at least about 40 percent by weight of said gum composition; C. the nicotine is present in said composition in an amount in the range of about 0.05 weight percent to about 2 weight percent based on the weight of the chewing gum base and calculated as the free base; D. the amount of nicotine distributed in said chewing gum base is in the range of about 1 to about 10 milligrams, such amount of nicotine approximating the amount available upon smoking a smoking tobacco product; E. the nicotine being present in said gum composition as a nicotine compound selected from the group consisting of a. a nicotine free base, b. a pharmacologically-acceptable salt of nicotine, and c. a nicotine-regenerative adsorbent complex comprising a compound selected from the group consisting of nicotine and a pharmacologically-acceptable salt of nicotine sorbed on a regenerative adsorbent; F. said chewing gum composition when chewed releasing nicotine in small and reduced amounts within a period of the first few minutes of chewing, and G. especially within the first ten minutes of chewing releasing the nicotine at a rate less than if the nicotine were present in an ordinary chewing gum composition, having a relatively low percentage of chewing gum base, that is, an amount constituting less than about 40 percent by weight of the gum composition.

Claim 8

NICOTINE, SUBSTANTIALLY UNIFORMLY DISTRIBUTED IN SAID CHEWING GUM BASE, WHEREIN: A. THE COMPOSITION IS IN THE FORM OF A CHEWABLE GUM UNIT WEIGHING IN THE RANGE OF ABOUT 0.5 TO ABOUT 4 GRAMS; B. THE CHEWING GUM BASE IS PRESENT IN SAID GUM COMPOSITION IN A RELATIVELY HIGH PERCENTAGE, THAT IS, AN AMOUNT CONSTITUTING AT LEAST ABOUT 40 PERCENT BY WEIGHT OF SAID GUM COMPOSITION; C. THE NICOTINE IS PRESENT IN SAID COMPOSITION IN AN AMOUNT IN THE RANGE OF ABOUT 0.05 WEIGHT OF THE CHEWING GUM WEIGHT PERCENT BASED ON THE WEIGHT OF THE CHEWING GUM BASE AND CALCULATED AS THE FREE BASE; D. THE AMOUNT OF NICOTINE DISTRIBUTED IN SAID CHEWING GUM A. A NICOTINE FREE BASE, SUCH AMOUNT OF NICOTINE APPROXIMATING THE AMOUNT AVAILABLE UPON SMOKING TOBACCO PRODUCT; E. THE NICOTINE BEING PRESENT IN SAID GUM COMPSOTION AS A NICOTINE COMPOUND SELECTED FROM THE GROUP CONSISTING OF A. A NICOTINE FREE BASE, B. A PHARMACOLOGICALLY-ACCEPTABLE SALT OF NICOTINE, AND C. A NICOTINE-REGENERATIVE ADSORBENT COMPLEX COMPRISING A COMPOUND SELECTED FROM THE GROUP CONSITING OF NICOTINE AND A PHARMACOLOGICALLY-ACCEPTABLE SALT OF NICOTINE SORBED ON A REGENERATIVE ADSORBENT; F. SAID CHEWING GUM COMPOSITION WHEN CHEWED RELEASING NICOTINE IN SMALL AND REDUCED AMOUNTS WITHIN A PERIOD OF THE FIRST FEW MINUTES OF CHEWING, AND G. ESPECIALLY WITHIN THE FIRST TEN MINUTES OF CHEWING RELEASING THE NICOTINE AT A RATE LESS THAN IF THE NICOTINE WERE PRESENT IN AN ORDINARY CHEWING GUM COMPOSITION, HAVING A RELATIVELY LOW PERCENTAGE OF CHEWING GUM BASE, THAT IS, AN AMOUNT CONSTITUTING LESS THAN ABOUT 40 PERCENT BY WEIGHT OF THE GUM COMPOSITION.

Claim 9

NICOTINE, SUBSTANTIALLY UNIFORMLY DISTRIBUTED IN SAID CHEWING GUM BASE, WHEREIN: A. THE COMPOSITION IS IN THE FORM OF A CHEWABLE GUM UNIT WEIGHING IN THE RANGE OF ABOUT 0.5 TO ABOUT 4 GRAMS; B. THE CHEWING GUM BASE IS PRESENT IN SAID GUM COMPOSITION IN A RELATIVELY HIGH PERCENTAGE, THAT IS, AN AMOUNT CONSTITUTING AT LEAST ABOUT 40 PERCENT BY WEIGHT OF SAID GUM COMPOSITION; C. THE NICOTINE IS PRESENT IN SAID COMPOSITION IN AN AMOUNT IN THE RANGE OF ABOUT 0.05 WEIGHT OF THE CHEWING GUM WEIGHT PERCENT BASED ON THE WEIGHT OF THE CHEWING GUM BASE AND CALCULATED AS THE FREE BASE; D. THE AMOUNT OF NICOTINE DISTRIBUTED IN SAID CHEWING GUM A. A NICOTINE FREE BASE, SUCH AMOUNT OF NICOTINE APPROXIMATING THE AMOUNT AVAILABLE UPON SMOKING TOBACCO PRODUCT; E. THE NICOTINE BEING PRESENT IN SAID GUM COMPSOTION AS A NICOTINE COMPOUND SELECTED FROM THE GROUP CONSISTING OF A. A NICOTINE FREE BASE, B. A PHARMACOLOGICALLY-ACCEPTABLE SALT OF NICOTINE, AND C. A NICOTINE-REGENERATIVE ADSORBENT COMPLEX COMPRISING A COMPOUND SELECTED FROM THE GROUP CONSITING OF NICOTINE AND A PHARMACOLOGICALLY-ACCEPTABLE SALT OF NICOTINE SORBED ON A REGENERATIVE ADSORBENT; F. SAID CHEWING GUM COMPOSITION WHEN CHEWED RELEASING NICOTINE IN SMALL AND REDUCED AMOUNTS WITHIN A PERIOD OF THE FIRST FEW MINUTES OF CHEWING, AND G. ESPECIALLY WITHIN THE FIRST TEN MINUTES OF CHEWING RELEASING THE NICOTINE AT A RATE LESS THAN IF THE NICOTINE WERE PRESENT IN AN ORDINARY CHEWING GUM COMPOSITION, HAVING A RELATIVELY LOW PERCENTAGE OF CHEWING GUM BASE, THAT IS, AN AMOUNT CONSTITUTING LESS THAN ABOUT 40 PERCENT BY WEIGHT OF THE GUM COMPOSITION.

Claim 10

The composition of claim 1, wherein the nicotine is present as a nicotine-regenerative adsorbent complex.