US3872226A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Tc{14 99m albumin aggregates with stannous tin and denatured albumin
Assignee: ER Squibb and Sons LLC
•
Filing: 1972-06-23
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Granted: 1975-03-18
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Expires: 1992-06-23
Abstract
Abstract Disclosed herein are aggregatess comprising coprecipitated Tc99m, ionic tin and denatured albumin. The aggregates of this invention can be utilized in the imaging of lungs to determine the conditin of pulmonary vessels.
Inventors
- 👤 Thomas Albert Haney
- 👤 Gerald Anthony Bruno
- 👤 Janeth Bartlett
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 17:03
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/14; A61K9/16; A61K9/1605; A61K9/1629; A61K9/1658; A61K51/00; A61K51/02; A61K51/04; A61K51/08; A61K51/081; A61K51/12; A61K51/1217; A61K51/1241; A61K51/1255; A61K2123/00
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
9 words
A MACROAGGREGATE OF TECHNETIUM-99M, DENATURED ALBUMIN AND STANNOUS TIN.
Claim 2
Dependent Claim
9 words
A MACROAGGREGATE OF TECHNETIUM-99M, DENATURED ALBUMIN AND STANNOUS TIN.
Claim 3
Dependent Claim
16 words
A macroaggregate in accordance with claim 1 being from about 5 to 100 microns in dimension.
Claim 4
Dependent Claim
41 words
A process for preparing macroaggregates of claim 1 which comprises complexing denatured albumin with a stannous salt, adjusting the pH of the reaction solution to from between about 4.8 to 5.8 to form macroaggregates and adding an aqueous Tc-99m solution thereto.
Claim 5
Dependent Claim
16 words
A process in accordance with claim 3 wherein the pH is adjusted with an inorganic base.
Claim 6
Dependent Claim
26 words
A process for preparing macroaggregates in accordance with claim 1 which comprises adding Technetium-99m to a reaction vial containing macroaggregates of denatured albumin and stannous tin.
Claim 7
Dependent Claim
20 words
The process of claim 3 wherein said macroaggregate solution is dehyrated prior to the addition of the aqueous Technetium-99m solution.
Claim 8
Dependent Claim
30 words
A method for scanning the lungs the pulmonary system which comprises injecting intravenously the macroaggregate of claim 1 in a pharmaceutically acceptable vehicle and scanning the lungs and pulmonary system.
Claim 9
Dependent Claim
11 words
A macroaggregate of Technetium-99m, denatured albumin or globulin, and stannous tin.
Claim 10
Dependent Claim
11 words
A macroaggregate of Technetium-99m, denatured albumin or globulin, and stannous tin.
Claim 11
Dependent Claim
30 words
A method for scanning the lungs and pulmonary system which comprises injecting intravenously the macroaggregates of claim 8 in a pharmaceutically acceptable vehicle and scanning the lungs and pulmonary system.
References Cited (Backward Citations)
US3725295A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-03-17 | 1978-09-16 | 1979-03-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-03-17 | 1982-09-16 | 1983-03-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-03-17 | 1986-09-16 | 1987-03-18 | $7700.00 | Window Closed / Lapsed |