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US3872121A Expired / Lapsed US ⏱️ 0.0 years remaining

2-(Phenyl-amino-2-imidazolines and salts thereof

Assignee: C.H. Boehringer Sohn AG and Co KG
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Filing: 1973-04-30
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Granted: 1975-03-18
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Expires: 1993-04-30
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Abstract

Abstract Compounds of the formula WHEREIN R1, R2 and R3, which may be identical to or different from each other, are each hydrogen, fluorine, chlorine, bromine, methyl, ethyl, ethoxy, trifluoromethyl or cyano, and R4 and R5, which must be different, are each hydrogen, WHERE R6 and R7, which may be identical to or different from each other, are each hydrogen, methyl or optionally substituted phenyl, or, together with each other, ethylene or propylene, R8 and R9, which may be identical to or different from each other, are each hydrogen, halogen, methyl or nitro, A is nitrogen or -CH-, and N IS 0 OR 1, AND NON-TOXIC, PHARMACOLOGICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF; THE COMPOUNDS AS WELL AS THE SALTS ARE USEFUL AS HYPOTENSIVES.

Inventors

  • 👤 Werner Kummer
  • 👤 Helmut Stahle
  • 👤 Herbert Koppe
  • 👤 Wolfgang Hoefke

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-25 21:04
CPC Classifications
C; C07; C07D; C07D233/00; C07D233/04; C07D233/28; C07D233/44; C07D233/50

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 5 words
A COMPOUND OF THE FORMULA
Claim 2
Dependent Claim 5 words
A COMPOUND OF THE FORMULA
Claim 3
Dependent Claim 18 words
A compound of claim 1, which is 1-(1,4,5,6-tetrahydro-pyrimidin-2-yl)-2-((2'',6''-dichloro-phenyl)-amino)-2 -imidazoline or a non-toxic, pharmacologically acceptable acid addition salt thereof.
Claim 4
Dependent Claim 17 words
A compound of claim 1, which is N-(2,6-dichloro-phenyl)-N-(4'',6''-dimethyl-pyrimidin-2''-yl)-N-(2-imidazolin-2-yl)-amine or a non-toxic, pharmacologically acceptable acid addition salt thereof.
Claim 5
Dependent Claim 17 words
A compound of claim 1, which is N-(2,6-dichloro-phenyl)-N-(2'',4''-dimethyl-pyrimidin-6''-yl)-N-(2-imidazolin-2-yl)-amine or a non-toxic, pharmacologically acceptable acid addition salt thereof.

References Cited (Backward Citations)

US2719846A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1978-03-17 1978-09-16 1979-03-18 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1982-03-17 1982-09-16 1983-03-18 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1986-03-17 1986-09-16 1987-03-18 $7700.00 Window Closed / Lapsed

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