N,N{40 -Heptamethylenebis(4-trifluoromethoxybenzamide)-{62 -cyclodextrin inclusion complex
Abstract
Abstract 4-(Q-O)-4''-R1-N,N''-alkylenebis(benzamides), N,N''alkylenebis(3,4-methylenedioxybenzamides) or N,N''-alkylenebis(4(lower-alkoxy)benzamides), having endocrinological properties, where Q is lower-alkyl, lower-alkoxyalkyl, lower-alkenyl, halolower-alkyl, halo-lower-alkenyl, lower-cycloalkyl, phenyl and BN(lower alkyl) where BN is di-(lower-alkyl)amino or a saturated Nheteromonocyclic radical having from five to seven ring atoms and alkylene has at least five carbon atoms between its two connecting linkages and R1 is Q-O-, hydrogen, lower-alkoxy, lower-alkyl, halo, benzyloxy, hydroxy, di-(lower-alkyl)amino, nitro, amino or trihalomethyl are prepared preferably by reacting the appropriate diamine or N-(aminoalkyl)-benzamide with two or one molar equivalents, respectively, of the appropriate benzoyl halide. The instant application relates particularly to N,N''heptamethylenebis(4-trifluoromethoxybenzamide)- Beta cyclodextrin inclusion complex, having antifertility activity.
Inventors
- 👤 George Y Lesher
Bibliographic Details
Claims Analysis
Total Claims: 2References Cited (Backward Citations)
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