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US3867431A Expired / Lapsed US ⏱️ 0.0 years remaining

Contrast agent for angiography and urography

Assignee: Bracco SpA
•
Filing: 1972-07-25
•
Granted: 1975-02-18
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Expires: 1992-07-25
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Abstract

Abstract 3-(N- Beta , gamma -dihydroxypropyl-acetyl-amino)-5acetylaminomethyl-2,4,6-triiodobenzoic acid and its non-toxic, water-soluble salts with alkali metals and amines are better tolerated by the central nervous system for intracerebral and intracisternal application than X-ray contrast agents available heretofore for cerebral angiography. They are preferentially excreted from the blood by the kidney in a manner to make them useful for urography.

Inventors

  • 👤 Ernst Felder
  • 👤 Davide Pitre
  • 👤 Hans Zutter

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-26 14:48
CPC Classifications
A; A61; A61K; A61K49/00; A61K49/04; A61K49/0433

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 10 words
A COMPOUND WHICH IS THE 3-(N--B,$DIHYDROXYPROPYLACETYLAMINO)-5ACETYLAMINOMETHYL-2,4,6TRIIODOBENZOIC ACID OF THE FORMULA
Claim 2
Dependent Claim 10 words
A COMPOUND WHICH IS THE 3-(N--B,$DIHYDROXYPROPYLACETYLAMINO)-5ACETYLAMINOMETHYL-2,4,6TRIIODOBENZOIC ACID OF THE FORMULA
Claim 3
Dependent Claim 12 words
A compound as set forth in claim 1 which is said acid.
Claim 4
Dependent Claim 21 words
A compound as set forth in claim 1 which is a salt of said acid with sodium, lithium, or an alkanolamine.
Claim 5
Dependent Claim 31 words
A compound as set forth in claim 1 which is a salt of said acid with an alkanolamine selected from the group consisting of N-methylglucamine, N-methylxylamine, 1-methylamino-2,3-propanediol, monoethanolamine, diethanolamine, and tris-(hydroxymethyl)-aminomethane.

References Cited (Backward Citations)

US3360436A Cited
US3702866A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1978-02-17 1978-08-19 1979-02-18 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1982-02-17 1982-08-19 1983-02-18 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1986-02-17 1986-08-19 1987-02-18 $7700.00 Window Closed / Lapsed

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