US3867424A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method for preparing acylated products
Assignee: KH Neochem Co Ltd
•
Filing: 1970-06-25
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Granted: 1975-02-18
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Expires: 1990-06-25
Abstract
Abstract Acylation of nitrogen containing compounds utilizing esters as acylation agents in the presence of salts of substituted pyridine compounds.
Inventors
- 👤 Yasuo Fujimoto
- 👤 Nobuhiro Nakamizo
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 17:51
CPC Classifications
C; C07; C07D; C07D239/00; C07D239/02; C07D239/24; C07D239/28; C07D239/46; C07D239/56; C07C; C07C243/00; C07C243/24; C07C243/38; C07C273/00; C07C273/18; C07C273/1809; C07C273/1836; C07D295/00; C07D295/16; C07D295/18; C07D295/182; C07D295/185; C07K; C07K1/00; C07K1/06; C07K1/08; C07K1/084
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
104 words
IN THE PROCESS FOR PREPARING A CARBOXYLIC ACID AMIDE WHEREIN A PRIMARY OR SECONDARY AMINE SELECTED FROM ALKYLAMINES, ARYLAMINES AND SUBSTITUTED ARYLAMINES IS ACYLATED WITH AN ESTER DERIVED FROM ALIPHATIC OR AROMATIC CARBOXYLIC ACID, THE IMPROVEMENT WHICH COMPRISES CARRYING OUT SAID ACYLATION IN THE PRESENCE OF AN ALKALI-METAL SALT, AN ALKALINE EARTH METAL SALT OF A QUATERNARY AMMONIUM SALT OF A COMPOUND CONTAINING A PYRIDINE NUCLEUS DIRECTLY SUBSTITUTED BY A HYDROXY GROUP, A MERCAPTO GROUP, OR A GROUP SELECTED FROM ALKYL GROUPS HAVING 1 TO 6 CARBON ATOMS, NITRO GROUPS, AND CYANO GROUPS HAVING 1 TO 6 CARBON ATOMS, NITRO GROUPS, AND CYANO GROUPS.
Claim 2
Dependent Claim
104 words
IN THE PROCESS FOR PREPARING A CARBOXYLIC ACID AMIDE WHEREIN A PRIMARY OR SECONDARY AMINE SELECTED FROM ALKYLAMINES, ARYLAMINES AND SUBSTITUTED ARYLAMINES IS ACYLATED WITH AN ESTER DERIVED FROM ALIPHATIC OR AROMATIC CARBOXYLIC ACID, THE IMPROVEMENT WHICH COMPRISES CARRYING OUT SAID ACYLATION IN THE PRESENCE OF AN ALKALI-METAL SALT, AN ALKALINE EARTH METAL SALT OF A QUATERNARY AMMONIUM SALT OF A COMPOUND CONTAINING A PYRIDINE NUCLEUS DIRECTLY SUBSTITUTED BY A HYDROXY GROUP, A MERCAPTO GROUP, OR A GROUP SELECTED FROM ALKYL GROUPS HAVING 1 TO 6 CARBON ATOMS, NITRO GROUPS, AND CYANO GROUPS HAVING 1 TO 6 CARBON ATOMS, NITRO GROUPS, AND CYANO GROUPS.
Claim 3
Dependent Claim
18 words
The process of claim 1 wherein the compound containing the pyridine nucleus is a quinoline or an isoquinoline.
Claim 4
Dependent Claim
12 words
The process of claim 1 wherein the carboxylic acid amide is benzyloxycarbonyl-L-valinebenzylamide.
Claim 5
Dependent Claim
15 words
The process of claim 1 wherein the salt is the sodium salt of 2-hydroxy pyridine.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-02-17 | 1978-08-19 | 1979-02-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-02-17 | 1982-08-19 | 1983-02-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-02-17 | 1986-08-19 | 1987-02-18 | $7700.00 | Window Closed / Lapsed |