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US3865948A Expired / Lapsed US ⏱️ 0.0 years remaining

Treatment of helminth infections with substituted phenyl-thioureas

Assignee: May and Baker Ltd
•
Filing: 1971-06-15
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Granted: 1975-02-11
•
Expires: 1991-06-15
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Abstract

Abstract Benzene derivatives of the formula: WHEREIN R represents an aliphatic hydrocarbon group optionally substituted by halogen or alkoxy, R1 represents hydrogen or methyl, and R2 represents hydrogen, halogen, alkyl, alkanoylamino optionally substituted by cycloalkyl of 3 to 6 carbon atoms, alkoxycarbonylamino, alkanoyl, benzoyl or N-methylmethanesulphonylamino, possess anthelmintic and anti-viral activity. New compounds within that formula also possess fungicidal properties.

Inventors

  • 👤 David Anthony Eichler
  • 👤 Joshua Michael Stuart Lucas
  • 👤 George Christopher Jame Martin
  • 👤 Edgar William Parnell
  • 👤 Garth Molesdale Thompson

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-07 21:17
CPC Classifications
C; C07; C07D; C07D295/00; C07D295/04; C07D295/14; C07C; C07C335/00; C07C335/04; C07C335/24; C07C335/28

Claims Analysis

Total Claims: 13
Claim 1
Independent Claim 37 words
METHOD FOR THE TREATMENT OF HELMINTH INFECTIONS IN MAN AND DOMESTIC ANIMALS WHICH COMPRISES ADMINSTERING TO MAN OR A DOMESTIC ANIMAL INFECTED WITH HELMINTHS AN ANTHELMINTICALLY EFFECTIVE AMOUNT OF AT LEAST ONE BENZENE DERIVATIVE OF THE FORMULA:
Claim 2
Dependent Claim 37 words
METHOD FOR THE TREATMENT OF HELMINTH INFECTIONS IN MAN AND DOMESTIC ANIMALS WHICH COMPRISES ADMINSTERING TO MAN OR A DOMESTIC ANIMAL INFECTED WITH HELMINTHS AN ANTHELMINTICALLY EFFECTIVE AMOUNT OF AT LEAST ONE BENZENE DERIVATIVE OF THE FORMULA:
Claim 3
Dependent Claim 18 words
Method according to claim 1 in which the man or domestic animal is infected with parasitic nematode worms.
Claim 4
Dependent Claim 14 words
Method according to claim 1 in which R represents methyl, ethyl, allyl or propargyl.
Claim 5
Dependent Claim 10 words
Method according to claim 1 in which R2 represents hydrogen.
Claim 6
Dependent Claim 18 words
Method according to claim 1 in which R represents methyl or ethyl and R1 and R2 represent hydrogen.
Claim 7
Dependent Claim 30 words
Method according to claim 1 in which the dose of benzene derivative administered to the man or domestic animal is 5 mg. to 1,000 mg. per kilogram of body weight.
Claim 8
Dependent Claim 30 words
Method according to claim 6 in which the dose of benzene derivative administered to the man or domestic animal is 25 mg. to 250 mg. per kilogram of body weight.
Claim 9
Dependent Claim 19 words
Method according to claim 1 in which the domestic animals treated are cattle, sheep, pigs, goats, poultry or equines.
Claim 10
Dependent Claim 17 words
Method according to claim 1 in which R is ethyl, R1 is hydrogen, and R2 is isopropoxycarbonylamino.
Claim 11
Dependent Claim 21 words
Medicated animal feedstuffs comprising an animal feedstuff and 0.001 to 3 percent by weight of a benzene derivative of the formula:
Claim 12
Dependent Claim 21 words
Medicated animal feedstuffs comprising an animal feedstuff and 0.001 to 3 percent by weight of a benzene derivative of the formula:
Claim 13
Dependent Claim 17 words
Medicated animal feedstuffs according to claim 10 which include, as auxiliary therapeutic agent, a fasciolicide or anthelmintic.

References Cited (Backward Citations)

FR2011165A1 Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1978-02-10 1978-08-12 1979-02-11 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1982-02-10 1982-08-12 1983-02-11 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1986-02-10 1986-08-12 1987-02-11 $7700.00 Window Closed / Lapsed

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