US3864329A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Penicillins substituted with heterocyclic groups
Assignee: Sumitomo Chemical Co Ltd
•
Filing: 1972-09-26
•
Granted: 1975-02-04
•
Expires: 1992-09-26
Abstract
Abstract A penicillin of the formula: WHEREIN A is a substituted or unsubstituted condensed aromatic carbocyclic or heterocyclic ring, R is hydrogen or lower alkyl, X is oxygen or sulfur, Y is hydrogen, lower alkyl, lower alkanoyl or lower alkoxycarbonyl and Z is phenyl or thienyl which can be produced by reacting 6-aminopenicillanic acid or its ester with a carboxylic acid of the formula: WHEREIN A, R, X, Y and Z are each as defined above or its reactive derivative. The said penicillin and its non-toxic salts have a broad antimicrobial spectrum against various gram-positive and gram-negative bacteria, and they exhibit characteristically a strong antimicrobial activity against Pseudomonas.
Inventors
- 👤 Hisao Tobiki
- 👤 Kozo Shimago
- 👤 Shigeru Okano
- 👤 Toshiaki Komatsu
- 👤 Toyozo Katsura
- 👤 Yasushi Taira
- 👤 Yasuko Eda
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 15:26
CPC Classifications
C; C07; C07D; C07D471/00; C07D471/02; C07D471/04; C07D215/00; C07D215/02; C07D215/16; C07D215/48; C07D215/54; C07D215/56; C07D499/00
Claims Analysis
Total Claims: 24
Claim 1
Independent Claim
5 words
A PENICILLIN OF THE FORMULA:
Claim 2
Dependent Claim
5 words
A PENICILLIN OF THE FORMULA:
Claim 3
Dependent Claim
3 words
D-(-)- Alpha -(7-Methyl-4-hydroxy-1,8-naphthyridine-3-carbonamido)-benzylpenicillin.
Claim 4
Dependent Claim
3 words
D-(-)- Alpha -(7-Methyl-4-hydroxy-1,8-naphthyridine-3-carbonamido)-benzylpenicillin.
Claim 5
Dependent Claim
4 words
D-(-)- Alpha -(6-Methylmercapto-4-hydroxy-1,5-naphthyridine-3-carbonamido) -benzylpenicillin.
Claim 6
Dependent Claim
4 words
D-(-)- Alpha -(6-Methylmercapto-4-hydroxy-1,5-naphthyridine-3-carbonamido) -benzylpenicillin.
Claim 7
Dependent Claim
4 words
D-(-)- Alpha -(6-Dimethylamino-4-hydroxy-1,5-naphthyridine-3-carbonamido) -benzylpenicillin.
Claim 8
Dependent Claim
4 words
D-(-)- Alpha -(6-Dimethylamino-4-hydroxy-1,5-naphthyridine-3-carbonamido) -benzylpenicillin.
Claim 9
Dependent Claim
3 words
D-(-)- Alpha -(4-Hydroxy-1,5-naphthyridine-3-carbonamido)-benzylpenicillin.
Claim 10
Dependent Claim
3 words
D-(-)- Alpha -(4-Hydroxy-1,5-naphthyridine-3-carbonamido)-benzylpenicillin.
Claim 11
Dependent Claim
3 words
D-(-)- Alpha -(6-Acetylamino-4-hydroxy-1,5-naphthyridine-3-carbonamido)-benzylpenicillin.
Claim 12
Dependent Claim
3 words
D-(-)- Alpha -(6-Acetylamino-4-hydroxy-1,5-naphthyridine-3-carbonamido)-benzylpenicillin.
Claim 13
Dependent Claim
3 words
D-(-)- Alpha -(6-Methyl-4-hydroxy-1,5-naphthyridine-3-carbonamido)-benzylpenicillin.
Claim 14
Dependent Claim
3 words
D-(-)- Alpha -(6-Methyl-4-hydroxy-1,5-naphthyridine-3-carbonamido)-benzylpenicillin.
Claim 15
Dependent Claim
3 words
D-(-)- Alpha -(6-Methylamino-4-hydroxy-1,5-naphthyridine-3-carbonamido)-benzylpenicillin.
Claim 16
Dependent Claim
3 words
D-(-)- Alpha -(6-Methylamino-4-hydroxy-1,5-naphthyridine-3-carbonamido)-benzylpenicillin.
Claim 17
Dependent Claim
4 words
D-(-)- Alpha -(6-Dimethylamino-4-hydroxy-1,5-naphthyridine-3-carbonamido)-2 -thienylmethylpenicillin.
Claim 18
Dependent Claim
4 words
D-(-)- Alpha -(6-Dimethylamino-4-hydroxy-1,5-naphthyridine-3-carbonamido)-2 -thienylmethylpenicillin.
Claim 19
Dependent Claim
3 words
D-(-)- Alpha -(4-Hydroxy-1,5-naphthyridine-3-carbonamido)-2-thienylmethylpenicillin.
Claim 20
Dependent Claim
3 words
D-(-)- Alpha -(4-Hydroxy-1,5-naphthyridine-3-carbonamido)-2-thienylmethylpenicillin.
Claim 21
Dependent Claim
3 words
D-(-)- Alpha -(6-Amino-4-hydroxy-1,5-naphthyridine-3-carbonamido)0-benzylpenicillin.
Claim 22
Dependent Claim
3 words
D-(-)- Alpha -(6-Amino-4-hydroxy-1,5-naphthyridine-3-carbonamido)0-benzylpenicillin.
Claim 23
Dependent Claim
3 words
D-(-)- Alpha -(4-Hydroxy-1,6-naphthyridine-3-carbonamido)-benzylpenicillin.
Claim 24
Dependent Claim
3 words
D-(-)- Alpha -(4-Hydroxy-1,6-naphthyridine-3-carbonamido)-benzylpenicillin.
References Cited (Backward Citations)
US3433784A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-02-03 | 1978-08-05 | 1979-02-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-02-03 | 1982-08-05 | 1983-02-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-02-03 | 1986-08-05 | 1987-02-04 | $7700.00 | Window Closed / Lapsed |