US3862332A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method of lowering serum cholesterol
Assignee: Dow Chemical Co
•
Filing: 1969-11-19
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Granted: 1975-01-21
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Expires: 1989-11-19
Abstract
Abstract Methods useful for lowering serum cholesterol in animals comprising administration to the animal of a hypocholesteremic amount of a bis(dialkylphenol) ketone mercaptole compound or a bis(dialkylphenol) mercaptal compound, preferably bis(3,5-ditert-butyl-4-hydroxyphenyl) acetone mercaptole, and compositions to be employed in practicing the method.
Inventors
- 👤 James W Barnhart
- 👤 Philip J Shea
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 13:00
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/095; A61K31/10
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
10 words
The method of claim 2 wherein R represents tertiary butyl.
Claim 2
Dependent Claim
11 words
The method of claim 1 wherein the compound is administered orally.
Claim 3
Dependent Claim
12 words
The method of claim 1 wherein the compound is bis(3,5-di-tert-butyl-4-hydroxyphenyl) acetone mercaptole.
Claim 4
Dependent Claim
12 words
The method of claim 1 wherein the compound is bis(3,5-di-tert-butyl-4-hydroxyphenyl) butanone mercaptole.
Claim 5
Dependent Claim
12 words
The method of claim 1 wherein the compound is bis(3-tert-butyl-4-hydroxy-5-isopropylphenyl) acetone mercaptole.
Claim 6
Dependent Claim
12 words
The method of claim 1 wherein the compound is bis(3-tert-butyl-4-hydroxy-5-methylphenyl) acetone mercaptole.
Claim 7
Dependent Claim
32 words
A composition for lowering serum cholesterol levels in animals comprising a pharmaCeutical carrier having incorporated therein from about 0.02 to about 90 percent by weight of a compound corresponding to the formula
Claim 8
Dependent Claim
12 words
The composition of claim 8 further comprising a surface active dispersing agent.
Claim 9
Dependent Claim
12 words
The composition of claim 8 wherein the compound is bis(3,5-di-tert-butyl-4-hydroxyphenyl) acetone mercaptole.
Claim 10
Dependent Claim
45 words
A composition for lowering serum cholesterol levels in animals, said composition being in dosage unit form adapted for administration to animals, each dosage unit containing from about 100 milligrams to about 5 grams per unit of a substituted ketone mercaptole compound corresponding to the formula
Claim 11
Dependent Claim
19 words
The composition of claim 11 wherein the dosage unit is in a form adapted for oral administration to animals.
Claim 12
Dependent Claim
9 words
The composition of claim 12 wherein R2 represents methyl.
Claim 13
Dependent Claim
12 words
The composition of claim 13 wherein the compound is bis(3,5-di-tert-butyl-4-hydroxyphenyl) acetone mercaptole.
Claim 14
Dependent Claim
19 words
The composition of claim 14 wherein the dosage unit is in a form adapted for oral administration to animals.
Claim 15
Dependent Claim
14 words
The composition of claim 15 wherein the pharmaceutical carrier comprises a surface-active dispersing agent.
References Cited (Backward Citations)
US3129262A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-01-20 | 1978-07-22 | 1979-01-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-01-20 | 1982-07-22 | 1983-01-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-01-20 | 1986-07-22 | 1987-01-21 | $7700.00 | Window Closed / Lapsed |