US3859429A
Expired / Lapsed
US
⏱️ 0.0 years remaining
M-iodohippuric acid labelled with radioactive iodine and process for its preparation
Assignee: Individual
•
Filing: 1972-07-07
•
Granted: 1975-01-07
•
Expires: 1992-07-07
Abstract
Abstract Novel m-iodohippuric acid labelled with radioactive iodine and the salts thereof with physiologically compatible bases are described as well as their use in kidney function studies and for kidney scanning.
Inventors
- 👤 Horst Hermann Elias
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 04:14
CPC Classifications
A; A61; A61K; A61K51/00
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
17 words
M-IODOHIPPURIC ACID LABELLED WITH RADIOACTIVE IODINE AND THE SALTS OF THE LABELLED ACID WITH PHYSIOLOGICALLY COMPATIBLE BASES.
Claim 2
Dependent Claim
17 words
M-IODOHIPPURIC ACID LABELLED WITH RADIOACTIVE IODINE AND THE SALTS OF THE LABELLED ACID WITH PHYSIOLOGICALLY COMPATIBLE BASES.
Claim 3
Dependent Claim
10 words
m-123Iodohippuric acid and the salts thereof with physiologically compatible bases.
Claim 4
Dependent Claim
10 words
m-123Iodohippuric acid and the salts thereof with physiologically compatible bases.
Claim 5
Dependent Claim
10 words
m-125Iodohippuric acid and the salts thereof with physiologically compatible bases.
Claim 6
Dependent Claim
10 words
m-125Iodohippuric acid and the salts thereof with physiologically compatible bases.
Claim 7
Dependent Claim
10 words
m-131Iodohippuric acid and the salts thereof with physiologically compatible bases.
Claim 8
Dependent Claim
10 words
m-131Iodohippuric acid and the salts thereof with physiologically compatible bases.
Claim 9
Dependent Claim
51 words
A process for the preparation of m-iodohippuric acid labelled with iodine, which comprises heating inactive m-iodohippuric acid in the molten state with sodium iodide or another metal iodide in which the iodine is radioactive to a temperature within the range of from 156* to 170*C, and then recovering the iodine-labelled acid.
Claim 10
Dependent Claim
51 words
A process for the preparation of m-iodohippuric acid labelled with iodine, which comprises heating inactive m-iodohippuric acid in the molten state with sodium iodide or another metal iodide in which the iodine is radioactive to a temperature within the range of from 156* to 170*C, and then recovering the iodine-labelled acid.
Claim 11
Dependent Claim
18 words
The process as claimed in claim 5, wherein the radioactively labelled sodium iodide is sodium123iodide, sodium-125iodide or sodium131iodide.
Claim 12
Dependent Claim
24 words
A process as claimed in claim 5 wherein the recovered iodine-labelled hippuric acid is salified by the addition thereto of a physiologically compatible base.
Claim 13
Dependent Claim
44 words
A pharmaceutical composition, adaptable to administration by injection for kidney function studies and for kidney scanning, said composition comprising m-iodohippuric acid labelled with radioactive iodine, or salts of the labelled acid with physiologically compatible bases, in combination with a physiologically tolerable liquid pharmaceutical diluent.
Claim 14
Dependent Claim
44 words
A pharmaceutical composition, adaptable to administration by injection for kidney function studies and for kidney scanning, said composition comprising m-iodohippuric acid labelled with radioactive iodine, or salts of the labelled acid with physiologically compatible bases, in combination with a physiologically tolerable liquid pharmaceutical diluent.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-01-06 | 1978-07-08 | 1979-01-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-01-06 | 1982-07-08 | 1983-01-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-01-06 | 1986-07-08 | 1987-01-07 | $7700.00 | Window Closed / Lapsed |