US3859338A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Derivatives of 4-(4'-biphenylyl)-3-or-2-butenoic acid and salts thereof
Assignee: Individual
•
Filing: 1972-09-14
•
Granted: 1975-01-07
•
Expires: 1992-09-14
Abstract
Abstract Compounds of the formula WHEREIN R1 and R3, may be identical to or different from each other, are each hydrogen or halogen, R2 is halogen, nitro, cyano, amino, (alkanoyl of 1 to 4 carbon atoms)-amino or, when R3 is halogen, also hydrogen, A is -C(R4) CH-CH2- or -CH(R4)-CH CH-, where R4 is hydrogen or alkyl of 1 to 2 carbon atoms, and X is hydroxyl, alkoxy of 1 to 4 carbon atoms or WHERE R5 and R6, which may be identical to or different from each other, are each hydrogen or alkyl of 1 to 3 carbon atoms, or one is hydroxyphenyl and the other is hydrogen, AND, WHEN X is -OH, non-toxic, pharmacologically acceptable salts thereof; the compounds as well as the salts are useful as antiphlogistics.
Inventors
- 👤 Wolfhard Engel
- 👤 Ernst Seeger
- 👤 Helmut Teufel
- 👤 Gunther Engelhardt
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 22:19
CPC Classifications
C; C07; C07C; C07C57/00; C07C57/52; C07C57/58; C07C57/60; C07C205/00; C07C205/49; C07C205/56
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
5 words
A COMPOUND OF THE FORMULA
Claim 2
Dependent Claim
5 words
A COMPOUND OF THE FORMULA
Claim 3
Dependent Claim
10 words
A compound of claim 1 which is of the formula
Claim 4
Dependent Claim
22 words
A compound of claim 1 which is trans-4-(2''''-fluoro-4''-biphenylyl)-3-butenoic acid or a non-toxic salt thereof with a pharmaceutically acceptable inorganic or organic base.
Claim 5
Dependent Claim
22 words
A compound of claim 1 which is cis-4-(2''''-fluoro-4''-biphenylyl)-3-butenoic acid or a non-toxic salt thereof with a pharmaceutically acceptable inorganic or organic base.
Claim 6
Dependent Claim
22 words
A compound of claim 1 which is trans-4-(2''-fluoro-4''-biphenylyl)-3-butenoic acid or a non-toxic salt thereof with a pharmaceutically acceptable inorganic or organic base.
Claim 7
Dependent Claim
22 words
A compound of claim 1 which is trans-4-(2''''-chloro-4''-biphenylyl)-3-butenoic acid or a non-toxic salt thereof with a pharmaceutically acceptable inorganic or organic base.
Claim 8
Dependent Claim
22 words
A compound of claim 1 which is trans-4-(2''-chloro-4''-biphenylyl)-3-butenoic acid or a non-toxic salt thereof with a pharmaceutically acceptable inorganic or organic base.
Claim 9
Dependent Claim
22 words
A compound of claim 1 which is trans-4-(2'',2''''-difluoro-4''-biphenylyl)-3-butenoic acid or a non-toxic salt thereof with a pharmaceutically acceptable inorganic or organic base.
Claim 10
Dependent Claim
22 words
A compound of claim 1 which is trans-4-(4''''-fluoro-4''-biphenylyl)-3-butenoic acid or a non-toxic salt thereof with a pharmaceutically acceptable inorganic or organic base.
Claim 11
Dependent Claim
22 words
A compound of claim 1 which is trans-4-(2'''',3''''-dichloro-4''-biphenylyl)-3-butenoic acid or a non-toxic salt thereof with a pharmaceutically acceptable inorganic or organic base.
Claim 12
Dependent Claim
22 words
A compound of claim 1 which is trans-4-(2'''',3''''-difluoro-4''-biphenylyl)-3-butenoic acid or a non-toxic salt thereof with a pharmaceutically acceptable inorganic or organic base.
Claim 13
Dependent Claim
22 words
A compound of claim 1 which is trans-4-(3''''-chloro-4''-biphenylyl)-3-butenoic acid or a non-toxic salt thereof with a pharmaceutically acceptable inorganic or organic base.
Claim 14
Dependent Claim
6 words
Trans-4-(2''-fluoro-4''-biphenylyl)-3-butenoic acid or its cyclohexylamine salt.
Claim 15
Dependent Claim
6 words
Trans-4-(2''-fluoro-4''-biphenylyl)-3-butenoic acid or its cyclohexylamine salt.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-01-06 | 1978-07-08 | 1979-01-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-01-06 | 1982-07-08 | 1983-01-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-01-06 | 1986-07-08 | 1987-01-07 | $7700.00 | Window Closed / Lapsed |