US3859305A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Indole aminoketones
Assignee: Evonik Operations GmbH
•
Filing: 1971-04-26
•
Granted: 1975-01-07
•
Expires: 1991-04-26
Abstract
Abstract THEIR SALTS AND QUATERNARY AMMONIUM COMPOUNDS, AS WELL AS THEIR OPTICALLY ACTIVE ISOMERS OR DIASTEREOMERS WHEREIN R1 to R4 represent hydrogen, halogen, lower alkyl, aralkyl, phenyl, hydroxyl, lower alkoxy, nitro or lower carboalkoxy, R5 and R6 are hydrogen or methyl, R7 and R8 are hydrogen, halogen or lower alkoxy, X is a heterocyclic ring system, mono- or condensed bicyclic, with 1 - 4 hetero atoms, in which the individual rings have 5 to 6 members and can also contain 1 or more carbonyl groups, Y is -CO-or -CH(OH)-. These compounds have pharmacological activity in that they increase the coronary blood flow by simultaneously causing dilation of the coronaries and an increase in contraction strength. Compounds of the formula
Inventors
- 👤 Klaus Posselt
- 👤 Kurt Thiele
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 04:01
CPC Classifications
C; C07; C07D; C07D307/00; C07D307/77; C07D307/78; C07D307/79; C07D307/81; C07D207/00; C07D207/02; C07D207/30; C07D207/34; C07D209/00; C07D209/02; C07D209/04; C07D209/10; C07D209/14; C07D217/00; C07D217/12; C07D217/14; C07D217/16; C07D217/22; C07D217/24; C07D231/00; C07D231/02; C07D231/10; C07D231/12; C07D231/14; C07D231/18; C07D231/20; C07D231/22; C07D307/02; C07D307/34; C07D307/38; C07D307/52; C07D307/56; C07D307/70; C07D307/71; C07D307/72; C07D307/73; C07D317/00; C07D317/08; C07D317/44; C07D317/46; C07D317/48; C07D317/50; C07D317/58; C07D319/00; C07D319/10; C07D319/14; C07D319/16; C07D319/18; C07D319/20; C07D333/00; C07D333/02; C07D333/04; C07D333/06; C07D333/22; C07D333/26; C07D333/28
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
5 words
A COMPOUND HAVING THE FORMULA:
Claim 2
Dependent Claim
5 words
A COMPOUND HAVING THE FORMULA:
Claim 3
Dependent Claim
17 words
A compound according to claim 1 wherein R9 is hydrogen and Y is in the 3 position.
Claim 4
Dependent Claim
17 words
A compound according to claim 2 wherein R5 is hydrogen, R6 is methyl and Y is -CO-.
Claim 5
Dependent Claim
11 words
A compound according to claim 3 wherein R4 is hydrogen methyl.
Claim 6
Dependent Claim
23 words
A compound according to claim 1 wherein R3 is H or methyl, R4 is H or methyl, and R9 is H or methoxy.
Claim 7
Dependent Claim
10 words
A compound according to claim 5 which is l-3(3-(3-phenyl-3-hydroxypropyl-(2)-amino)-propionyl)-1-methyl indole.
Claim 8
Dependent Claim
9 words
A compound according to claim 4 which is l-3-(3-(3-phenyl-3-hydroxypropyl-(2)-amino)-propionyl)-indole.
Claim 9
Dependent Claim
10 words
A compound according to claim 4 which is l-3-(3-(3-phenyl-3-hydroxypropyl-(2)-amino)-propionyl)-1,2-dimethyl indole.
Claim 10
Dependent Claim
17 words
A compound according to claim 1 wherein R9 is methoxy and Y is in the 3 position.
Claim 11
Dependent Claim
10 words
A compound according to claim 9 which is l-3-(3-(3-phenyl-3-hydroxypropyl-(2)-amino)-propionyl)-2-methyl-5-methoxy indole
Claim 12
Dependent Claim
13 words
A compound accordinG to claim 1 wherein Y is in the 3 position.
Claim 13
Dependent Claim
13 words
A compound according to claim 1 wherein Y is in the 2 position.
Claim 14
Dependent Claim
10 words
A compound according to claim 12 wherein R4 is methyl.
Claim 15
Dependent Claim
10 words
A compound according to claim 13 wherein Y is -CO-.
References Cited (Backward Citations)
US3371098A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-01-06 | 1978-07-08 | 1979-01-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-01-06 | 1982-07-08 | 1983-01-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-01-06 | 1986-07-08 | 1987-01-07 | $7700.00 | Window Closed / Lapsed |