Topical medicament kit with interlocking components

Claim 1

A kit for the sanitary preparation of a solution of predetermined concentration of a substance unstable in said solution comprising: a. a small sealed glass vial having an annular collar and a neck of reduced diameter at its open upper end; b. said vial containing a measured amount of said substance in concentrated form; and c. a larger sealed resilient plastic bottle having an annular collar and a neck of reduced diameter at its open upper end; d. said bottle containing a measured amount of a diluent for said concentrated substance; e. the diameter of the annular collar of said glass vial being slightly different than the diameter of the annular collar of said plastic bottle so that the annular collar of said glass vial can be engaged with the neck of said plastic bottle in piggyback arrangement so that the contents of the vial and bottle can be shaken without spillage; and f. the pressure within the piggyback arrangement can be altered by manual compression of the walls of said resilient plastic bottle, to accelerate the formation of said solution of predetermined concentration.

Claim 5

A method of utilizing a kit for the sanitary preparation of a solution of predetermined concentration of a substance unstable in solution, such kit comprising (1) a small sealed vial having an annular collar and a neck of reduced diameter at its upper end and containing a concentrated substance, and (2) a larger sealed resilient plastic bottle having an annular collar and a neck of reduced diameter at its upper end and containing a pharmaceutically acceptable diluent for dissolving the concentrated substance, the method comprising the steps of: a. removing the seals on said vial and said bottle; b. inverting the vial and then inserting the collar of the vial into a force fit relationship with the neck of the bottle so that the vial is retained atop the bottle in piggyback relationship; c. repeatedly rotating the interlocked vial and bottle until the contents of the vial are completely dissolved in the diluent in the bottle; and d. applying manual pressure to the walls of the resilient plastic bottle, as necessary, to accelerate the dissolving of the contents of the vial in the diluent in the bottle.

Claim 6

A method of utilizing a kit for the sanitary preparation of a solution of predetermined concentration of a substance unstable in solution, such kit comprising (1) a small sealed vial having an annular collar and a neck of reduced diameter at its upper end and containing a concentrated substance, and (2) a larger sealed resilient plastic bottle having an annular collar and a neck of reduced diameter at its upper end and containing a pharmaceutically acceptable diluent for dissolving the concentrated substance, the method comprising the steps of: a. removing the seals on said vial and said bottle; b. inverting the vial and then inserting the collar of the vial into a force fit relationship with the neck of the bottle so that the vial is retained atop the bottle in piggyback relationship; c. repeatedly rotating the interlocked vial and bottle until the contents of the vial are completely dissolved in the diluent in the bottle; and d. applying manual pressure to the walls of the resilient plastic bottle, as necessary, to accelerate the dissolving of the contents of the vial in the diluent in the bottle.

Claim 7

A method of utilizing a kit for the topical application of a medicament which is unstable when diluted, such kit comprising (1) a small sealed vial having an annular collar and a neck of reduced diameter at its upper end and containing a concentrated substance, (2) a larger sealed resilient plastic bottle having an annular collar and a neck of reduced diameter at its upper end and containing a pharmaceutically acceptable diluent for dissolving the concentrated substance, and (3) an applicator including a nozzle at the one end thereof and an annular skirt at the opposite end thereof for dispensing the dissolved concentrated substance, the method comprising the steps of: a. removing the seals on said vial and said bottle; b. inverting the vial and then inserting the collar of the vial into a force fit relationship with the neck of the bottle so that the vial is retained atop the bottle in piggyback relationship; c. repeatedly rotating the interlocked vial and bottle until the contents of the vial are completely dissolved in the diluent in the bottle; d. removing the vial from atop the bottle; e. inserting the skirt of the applicator into a force fit relationship with the neck of the bottle so that the applicator is retained atop the bottle; and f. squeezing the bottle to dispense the dissolved concentrated substance through the nozzle in drop-like fashion.

Claim 8

A method of utilizing a kit for the topical application of a medicament which is unstable when diluted, such kit comprising (1) a small sealed vial having an annular collar and a neck of reduced diameter at its upper end and containing a concentrated substance, (2) a larger sealed resilient plastic bottle having an annular collar and a neck of reduced diameter at its upper end and containing a pharmaceutically acceptable diluent for dissolving the concentrated substance, and (3) an applicator including a nozzle at the one end thereof and an annular skirt at the opposite end thereof for dispensing the dissolved concentrated substance, the method comprising the steps of: a. removing the seals on said vial and said bottle; b. inverting the vial and then inserting the collar of the vial into a force fit relationship with the neck of the bottle so that the vial is retained atop the bottle in piggyback relationship; c. repeatedly rotating the interlocked vial and bottle until the contents of the vial are completely dissolved in the diluent in the bottle; d. removing the vial from atop the bottle; e. inserting the skirt of the applicator into a force fit relationship with the neck of the bottle so that the applicator is retained atop the bottle; and f. squeezing the bottle to dispense the dissolved concentrated substance through the nozzle in drop-like fashion.