US3856853A
Expired / Lapsed
US
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Iodinated 5-substituted-1,3-benzenediacrylic and dipropionic acids
Assignee: STWB Inc
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Filing: 1971-03-29
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Granted: 1974-12-24
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Expires: 1991-03-29
Abstract
Abstract 5-Amino- or 5-hydroxy-2,4,6-triiodo-1,3-benzenediacrylic and dipropionic acids, optionally substituted by lower-alkyl or phenyl in the Alpha - and Alpha ''-positions, are prepared by iodination of the appropriate 5-amino- or 5-hydroxy-1,3benzenediacrylic or -dipropionic acids; and the 5-amino and 5hydroxy groups are further substituted by acyl and alkyl groups. The iodinated compounds are useful as intravenous cholecystographic agents.
Inventors
- 👤 J Ackerman
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 08:31
CPC Classifications
C; C07; C07C; C07C205/00; C07C205/49; C07C205/56; A; A61; A61K; A61K49/00; A61K49/04; A61K49/0433; C07C59/00; C07C59/40; C07C59/42; C07C59/56
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
5 words
A COMPOUND OF THE FORMULA
Claim 2
Dependent Claim
5 words
A COMPOUND OF THE FORMULA
Claim 3
Dependent Claim
11 words
A compound according to claim 1 wherein Y is -CH C(R'')-.
Claim 4
Dependent Claim
10 words
A compound according to claim 1 wherein Y is -CH2-CH(R'')-.
Claim 5
Dependent Claim
10 words
A compound according to claim 2 wherein R is H2N.
Claim 6
Dependent Claim
10 words
A compound according to claim 3 wherein R is H2N.
Claim 7
Dependent Claim
14 words
5-Butyramido-2,4,6-triiodo-1,3-benzenedipropionic acid, according to claim 3 wherein R is butyramido and R'' is hydrogen.
Claim 8
Dependent Claim
14 words
5-(N-Propylacetamido)-2,4,6-triiodo-1,3-benzenedipropionic acid, according to claim 3 wherein R is N-propylacetamido and R'' is hydrogen.
Claim 9
Dependent Claim
18 words
5-Acetamido-2,4,6-triiodo- Alpha , Alpha ''-diphenyl-1,3-benzenedipropionic acid, according to claim 3 wherein R is acetamido and R'' is phenyl.
Claim 10
Dependent Claim
18 words
5-Acetamido-2,4,6-triiodo- Alpha , Alpha ''-diethyl-1,3-benzenediacrylic acid, according to claim 2 wherein R is acetamido and R'' is ethyl.
Claim 11
Dependent Claim
18 words
5-Acetamido-2,4,6-triiodo- Alpha , Alpha ''-dibutyl-1,3-benzenediacrylic acid, according to claim 2 wherein R is acetamido and R'' is butyl.
Claim 12
Dependent Claim
5 words
A compound of the formula
Claim 13
Dependent Claim
5 words
A compound of the formula
Claim 14
Dependent Claim
10 words
3-(2-Carboxy-1-hydroxyethyl)-5-nitrocinnamic acid, according to claim 11 wherein R'''' is hydrogen.
Claim 15
Dependent Claim
10 words
3-(2-Carboxy-1-ethoxyethyl)-5-nitrocinnamic acid, according to claim 11 wherein R'''' is ethyl.
References Cited (Backward Citations)
US3128301A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1977-12-23 | 1978-06-24 | 1978-12-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1981-12-23 | 1982-06-24 | 1982-12-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1985-12-23 | 1986-06-24 | 1986-12-24 | $7700.00 | Window Closed / Lapsed |