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US3856789A Expired / Lapsed US ⏱️ 0.0 years remaining

Bis-basic ketones of thioxanthene

Assignee: Richardson Vicks Inc
•
Filing: 1971-04-23
•
Granted: 1974-12-24
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Expires: 1991-04-23
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Abstract

Abstract The novel bis-basic ketones of thioxanthene have antiviral activity when administered orally and parenterally. These compounds are represented by the following formula: WHEREIN A is a straight or branched alkylene chain having from 1 to about 6 carbon atoms; and each Y is A. the group WHEREIN R1 and R2 are individually hydrogen, allyl or lower alkyl having from 1 to about 4 carbon atoms; or B. the group WHEREIN N IS A WHOLE INTEGER OF 4 OR 5, AND R3 is hydrogen or lower alkyl having from 1 to about 4 carbon atoms and can be linked to any one of the carbon atoms of the heterocyclic group; or C. the group WHEREIN X is oxygen or NR4, and R4 is hydrogen or lower alkyl of from 1 to about 4 carbon atoms; OR PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS OF SAID BASE. These new compounds can be prepared by several different methods which are described.

Inventors

  • 👤 R Fleming
  • 👤 A Sill

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-27 19:24
CPC Classifications
C; C07; C07D; C07D335/00; C07D335/04; C07D335/10; C07D335/12

Claims Analysis

Total Claims: 17
Claim 1
Independent Claim 9 words
A COMPOUND SELECTED FROM A BASE OF THE FORMULA
Claim 2
Dependent Claim 9 words
A COMPOUND SELECTED FROM A BASE OF THE FORMULA
Claim 3
Dependent Claim 9 words
A compound of claim 1 wherein one of the
Claim 4
Dependent Claim 11 words
A compound of claim 2 wherein each Y is the group
Claim 5
Dependent Claim 11 words
A compound of claim 2 wherein each Y is the group
Claim 6
Dependent Claim 11 words
A compound of claim 4 wherein n is the integer 5.
Claim 7
Dependent Claim 11 words
A compound of claim 2 wherein each Y is the group
Claim 8
Dependent Claim 9 words
A compound of claim 6 wherein X is oxygen.
Claim 9
Dependent Claim 16 words
A compound of claim 2 which is 2,7-bis(2-(diethylamino)acetyl)thioxanthene or a pharmaceutically acceptable acid addition salt thereof.
Claim 10
Dependent Claim 16 words
A compound of claim 2 which is 2,7-bis(3-(diethylamino)propionyl)thioxanthene or a pharmaceutically acceptable acid addition salt thereof.
Claim 11
Dependent Claim 16 words
A compound of claim 2 which is 2,7-bis(4-(diethylamino)butyryl)thioxanthene or a pharmaceutically acceptable acid addition salt thereof.
Claim 12
Dependent Claim 16 words
A compound of claim 2 which is 2,7-bis(4-piperidinobutyryl)thioxanthene or a pharmaceutically acceptable acid addition salt thereof.
Claim 13
Dependent Claim 16 words
A compound of claim 2 which is 2,7-bis(4-morpholinobutyryl)thioxanthene or a pharmaceutically acceptable acid addition salt thereof.
Claim 14
Dependent Claim 16 words
A compound of claim 2 which is 2,7-bis(5-(dimethylamino)valeryl)thioxanthene or a pharmaceutically acceptable acid addition salt thereof.
Claim 15
Dependent Claim 16 words
A compound of claim 2 which is 2,7-bis(5-piperidinovaleryl)thioxanthene or a pharmaceutically acceptable acid addition salt thereof.
Claim 16
Dependent Claim 16 words
A compound of claim 2 which is 2,7-bis(5-(diethylamino)valeryl)thioxanthene or a pharmaceutically acceptable acid addition salt thereof.
Claim 17
Dependent Claim 16 words
A compound of claim 2 which is 2,7-bis(5-(diallylamino)valeryl)thioxanthene or a pharmaceutically acceptable acid addition salt thereof.

References Cited (Backward Citations)

US3767674A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1977-12-23 1978-06-24 1978-12-24 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1981-12-23 1982-06-24 1982-12-24 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1985-12-23 1986-06-24 1986-12-24 $7700.00 Window Closed / Lapsed

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