US3853862A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Production of 4-hydroxy-1,2-benzothiazine-3-carboxamides
Assignee: Pfizer Inc
•
Filing: 1973-04-23
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Granted: 1974-12-10
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Expires: 1993-04-23
Abstract
Abstract A process for the synthesis of N-aryl-3,4-dihydro-2-alkyl-4-oxo2H-1,2-benzothiazine-3-carboxamide 1,1-dioxides by treatment of N-aryl-N''-alkyl-N''-(2''alkoxycarbonylbenzenesulfonyl)glycineamides, useful intermediates for said process, with an alkali or alkaline earth metal hydride in a reaction-inert solvent at 50*-150* C., said products being antiinflammatory agents.
Inventors
- 👤 J Lombardino
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 21:06
CPC Classifications
C; C07; C07D; C07D213/00; C07D213/02; C07D213/04; C07D213/60; C07D213/72; C07D213/75; C07C; C07C271/00; C07C271/06; C07C271/08; C07C271/10; C07C271/22; C07D261/00; C07D261/02; C07D261/06; C07D261/10; C07D261/14; C07D277/00; C07D277/02; C07D277/20; C07D277/32; C07D277/38; C07D277/44; C07D277/46
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
11 words
A PROCESS FOR THE PREPARATION OF A COMPOUND OF THE FORMULA:
Claim 2
Dependent Claim
11 words
A PROCESS FOR THE PREPARATION OF A COMPOUND OF THE FORMULA:
Claim 3
Dependent Claim
12 words
The process of claim 1 wherein the metal hydride is sodium hydride.
Claim 4
Dependent Claim
10 words
The process of claim 2 wherein the solvent is tetrahydrofuran.
Claim 5
Dependent Claim
16 words
The process of claim 3 wherein X is hydrogen, and R2 and R3 are each methyl.
Claim 6
Dependent Claim
9 words
The process of claim 4 wherein R1 is phenyl.
Claim 7
Dependent Claim
9 words
The process of claim 4 wherein R1 is 2-thiazolyl.
Claim 8
Dependent Claim
9 words
The process of claim 4 wherein R1 is 6-methyl-2-pyridyl.
Claim 9
Dependent Claim
9 words
The process of claim 4 wherein R1 is 2-pyridyl.
References Cited (Backward Citations)
US3591584A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1977-12-09 | 1978-06-10 | 1978-12-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1981-12-09 | 1982-06-10 | 1982-12-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1985-12-09 | 1986-06-10 | 1986-12-10 | $7700.00 | Window Closed / Lapsed |