US3853468A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method and apparatus for clinical testing of biological fluids
Assignee: Individual
•
Filing: 1972-05-08
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Granted: 1974-12-10
•
Expires: 1992-05-08
Abstract
Abstract Biological fluids, such as blood sera, are placed individually on a testing surface like an acrylic coating alongside or in between control sera. The coating has an affinity for nonagglutinated particles. To each of the serum areas a drop of testing reagent is added and mixed. The mixtures are allowed to incubate or mature for approximately 5 to 10 minutes. An absorbent material is then applied to the test surface to remove the agglutinated particles of the mixtures from the test surface. The test area is then compared for density with the control areas and the results recorded. A preferred recordation is to dry and file the test surface upon which the serum has been tested.
Inventors
- 👤 H Haymond
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 08:23
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; Y; Y10; Y10S; Y10S436/00; Y10S436/807; Y10S436/809; Y10S436/811; Y10S436/812
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
125 words
A PROCESS FOR CLINICAL TESTING OF BIOLOGICAL FLUIDS BY MEANS OF A BUFFERED REAGENT TENDING TO AGGLUTINATE WITH BIOLOGICAL FLUID COMPONENTS UNDER CERTAIN KNOWN CONDITIONS AND INCLUDING THE STEPS OF ADDING A SAMPLE OF THE FLUID TO BE TESTED TO A TEST SURFACE HAVING AN AFFINITY FOR NONAGGLUTINATED PARTICLES, ADDING A SAMPLE OF CONTROL FLUID OF KNOWN CONTENT TO ANOTHER AREA OF THE TEST SURFACE, ADDING A REAGENT TO EACH OF THE TEST AND CONTROL FLUIDS ON THE TEST SURFACE, STIRRING EACH OF THE RESULTING MIXTURES, LEAVING THE MIXTURES UNDISTURBED FOR A REACTANT PERIOD, APPLYING AN ABSORBEND SECOND SURFACE TO THE AREAS ON THE TEST SURFACE, AND REMOVING THE SECOND SURFACE IN ORDER TO COMPARE THE TEST AND CONTROL AREAS ON ONE OF THE SURFACES.
Claim 2
Dependent Claim
125 words
A PROCESS FOR CLINICAL TESTING OF BIOLOGICAL FLUIDS BY MEANS OF A BUFFERED REAGENT TENDING TO AGGLUTINATE WITH BIOLOGICAL FLUID COMPONENTS UNDER CERTAIN KNOWN CONDITIONS AND INCLUDING THE STEPS OF ADDING A SAMPLE OF THE FLUID TO BE TESTED TO A TEST SURFACE HAVING AN AFFINITY FOR NONAGGLUTINATED PARTICLES, ADDING A SAMPLE OF CONTROL FLUID OF KNOWN CONTENT TO ANOTHER AREA OF THE TEST SURFACE, ADDING A REAGENT TO EACH OF THE TEST AND CONTROL FLUIDS ON THE TEST SURFACE, STIRRING EACH OF THE RESULTING MIXTURES, LEAVING THE MIXTURES UNDISTURBED FOR A REACTANT PERIOD, APPLYING AN ABSORBEND SECOND SURFACE TO THE AREAS ON THE TEST SURFACE, AND REMOVING THE SECOND SURFACE IN ORDER TO COMPARE THE TEST AND CONTROL AREAS ON ONE OF THE SURFACES.
Claim 3
Dependent Claim
37 words
A process in accordance with claim 1 wherein the test surface comprises a synthetic material taken from the group of acrylic, poly vinyl chloride, polyethylene, fluorinated polycarbonate, polycarbonate, vinyl latex, acrylic latex, polystyrene, polypropylene and nylon plastic.
Claim 4
Dependent Claim
22 words
A process in accordance with claim 1 including the further step of placing a diluent on each area of the test surface.
Claim 5
Dependent Claim
13 words
A process in accordance with claim 3 wherein the diluent is distilled water.
Claim 6
Dependent Claim
119 words
A process for clinical testing of biological fluids by means of a buffered reagent tending to agglutinate with biological fluid components under certain known conditions and including the steps of adding a diluent to two or more areas of a surface having an affinity for nonagglutinated particles, adding a drop of biological fluid to be tested to one of the test surface areas, adding control fluid of known content to another of the areas, adding a reagent to each of the test and control fluids, stirring each of the diluent and fluid mixtures, setting aside the mixtures for a reactant period, blotting the mixture areas, comparing the resultant blotted test and control areas, and recording the correlation data thereof.
Claim 7
Dependent Claim
119 words
A process for clinical testing of biological fluids by means of a buffered reagent tending to agglutinate with biological fluid components under certain known conditions and including the steps of adding a diluent to two or more areas of a surface having an affinity for nonagglutinated particles, adding a drop of biological fluid to be tested to one of the test surface areas, adding control fluid of known content to another of the areas, adding a reagent to each of the test and control fluids, stirring each of the diluent and fluid mixtures, setting aside the mixtures for a reactant period, blotting the mixture areas, comparing the resultant blotted test and control areas, and recording the correlation data thereof.
Claim 8
Dependent Claim
13 words
A process in accordance with claim 5 wherein the diluent is distilled water.
Claim 9
Dependent Claim
13 words
A process in accordance with claim 5 wherein the diluent is an antiserum.
Claim 10
Dependent Claim
22 words
A process in accordance with claim 5 wherein the reactant period the mixtures are set aside is from one to thirty minutes.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1977-12-09 | 1978-06-10 | 1978-12-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1981-12-09 | 1982-06-10 | 1982-12-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1985-12-09 | 1986-06-10 | 1986-12-10 | $7700.00 | Window Closed / Lapsed |