Bone seeking technetium 99m stannous phosphate complex
Abstract
Abstract A metabolizable radioactive technetium-99m-stannous-ring phosphate complex in which at least 15 to 20% by weight, and preferably 40 to 100%, of the phosphate moiety is a ring or cyclic phosphate of molecular weight less than 300 and in which no more than 5 to 15% or 20% by weight of such phosphate moiety is a linear polyphosphate of molecular weight greater than pyrophosphate, a method of making the same, a method of using the same by in vivo intravenous administration to a mammal of the sterile-non-pyrogenic complex followed by radioassay scanning or imaging the skeletal structure, and a kit made up of a stannousphosphate complex in which at least 15 to 20% and preferably 40 to 99% of the phosphate moiety is the aforesaid ring or cyclic phosphate and in which no more than 5 to 15% or 20% by weight of such phosphate moiety is a linear polyphosphate of molecular weight greater than pyrophosphate.
Inventors
- 👤 N Adler
- 👤 L Gamin
Bibliographic Details
Claims Analysis
Total Claims: 11References Cited (Backward Citations)
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