Isothiocyanobenzazoles

Abstract

Abstract 1. A COMPOUND OF THE GENERAL FORMULA 1,2-(-X-C(-(Y)N-R1)=N-),R2,(S=C=N-)-BENZENE WHEREIN THE SCN- GROUP IS IN THE 4-, 5-, 6- OR 7-POSITION, R1 REPRESENTS HYDROGEN, A STRAIGHT-CHAIN OR BRANCHED ALKYL OR ALKENYL RADICAL HAVING AT MOST 17 CARBON ATOMS, AN ALKYL OR ALKENYL RADICAL HAVING A TOTAL OF AT MOST 6 CARBON ATOMS AND SUBSTITUTED BY HALOGEN, -CN, -OH, C1-C5 ALKOXY, C1-C5 ALKYLTHIO OR DI(C1-C5)ALKYLAMINO, AN OPTIONALLY C1-C5 ALKYL-SUBSTITUTED MONO-, BI- OR TRICYCLIC CYCLOALKYL OR CYCLOALKENYL RADICAL HAVING 3 TO 10 CARBON ATOMS IN THE RING STRUCTURE, WHICH CAN ALSO BE BOUND BY WAY OF A CH2- GROUP TO THE SUBSTITUENT Y OR TO THE 2-POSITION OF THE HETEROCYCLC, R2 REPRESENTS HYDROGEN HALOGEN OR AN ALKYL OR ALKOXY RADICAL HAVING AT MOST 4 CARBON ATOMS, X REPRESENTS OXYGEN, SULPHUR OR >N-R3 R3 REPRESENTS HYDROGEN, AN ALKYL OR ALKENYL RAICAL HAVING AT MOST 5 CARBON ATOMS, A PHENYL OR BENZYL RADICAL, A DIMETHYLAMINO- OR DIETHYLAMINO-ALKYL RADICAL HAVING 2-5 CARBON ATOMS IN THE ALKYL CHAIN, AN ALKOXYCARBONYL RADICAL HAVING 2-5 CARBON ATOMS, ACETYL, PROPIONYL, TRICHLOROACETYL, BENZOYL, OR A C4-C7 SACCHARIDE GROUP, Y REPRESENTS OXYGEN, SLPHUR, -SO-, -NR4, -, -SO2-, OR N I THE NUMBER 0 OR 1, R4 REPRESENTS HYDROGEN, AN ALKYL OR ALKENYL RADICAL HAVING AT MOST 5 CARBON ATOMS, OR TOGETHER WITH THE NATOM AND THE SUBSTITUENT R1 A SATURATED OR UNSATURATED HETEROCYCLE HAVING 4 TO 6 CARBON AOMS WHICH MAY ALSO CONTAIN A FURTHER HETERO ATOM O OTOMS WHICH LEC ED FROM THE GROUP CONSISTING OF PYRROLIDINE, PIPERIDINE, 2-METHYLPIPERIDINDE, 4-METHYLPIPERIDINE, PIPERAZINE, N''-METHYL, N'',N''-DI-METHYL AND N''-ETHYL PIPERAZINE, MORPHOLINE, ISOMORPHOLINE, THIOMORPHOLINE AND HEXAMETHYLENEIMINE, OR THE GROUP >N-R5 AND R5 STANDS FOR HYDROGEN, METHYL OR ETHYL AND THEIR ACID ADDITION SALTS NON-TOXIC FOR WARM-BLODDED ANIMALS.

Inventors

• 👤 J Gallay
• 👤 R Bosshard
• 👤 P Brenneisen

Bibliographic Details