US3846490A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method of producing zeta-aminolevulinic acid hydrochloride
Assignee: Individual
•
Filing: 1972-03-01
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Granted: 1974-11-05
•
Expires: 1992-03-01
Abstract
Abstract A method of producing delta -aminolevulinic acid hydrochloride comprises acylating hippuric acid with monosuccinate acylchloride in the medium of 65 -picoline, subjecting the thusobtained c-acyl derivative to hydrolysis and isolating the final product. delta -Aminolevulinic acid hydrochloride can find application in the biosynthesis of vitamin B12.
Inventors
- 👤 N Makhova
- 👤 S Zavyalov
- 👤 J Volkenshtein
- 👤 G Kunitskaya
- 👤 N Aronova
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 14:56
CPC Classifications
C; C07; C07D; C07D263/00; C07D263/02; C07D263/30; C07D263/34; C07D263/36; C07D263/42
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
45 words
A METHOD OF PRODUCING $-AMINOLEVULINIC ACID HYDROCHLORIDE COMPRISING THE STEPS OF ACYLATING HIPPURIC ACID WITH MONOSUCCINATE ACYL CHLORIDE IN A MEDIUM OF Y-PICOLINE AT A TEMPERATURE OF -5* TO 0*C TO FORM A C-ACYL DERIVATIVE, HYDROLYZING THE C-ACYL DERIVATIVE AND ISOLATING THE &-AMINOLEVULINIC ACID HYDROCHLORIDE.
Claim 2
Independent Claim
45 words
A METHOD OF PRODUCING $-AMINOLEVULINIC ACID HYDROCHLORIDE COMPRISING THE STEPS OF ACYLATING HIPPURIC ACID WITH MONOSUCCINATE ACYL CHLORIDE IN A MEDIUM OF Y-PICOLINE AT A TEMPERATURE OF -5* TO 0*C TO FORM A C-ACYL DERIVATIVE, HYDROLYZING THE C-ACYL DERIVATIVE AND ISOLATING THE &-AMINOLEVULINIC ACID HYDROCHLORIDE.
Claim 3
Dependent Claim
40 words
A method according to claim 1 wherein the delta -aminolevulinic acid hydrochloride is isolated by dissolving the product of the hydrolysis step in concentrated hydrochloric acid and adding acetone to the acid solution to precipitate the delta -aminolevulinic acid hydrochloride.
References Cited (Backward Citations)
SU266773A1
Cited
GB1049770A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1977-11-04 | 1978-05-06 | 1978-11-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1981-11-04 | 1982-05-06 | 1982-11-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1985-11-04 | 1986-05-06 | 1986-11-05 | $7700.00 | Window Closed / Lapsed |