Patent US4113230A successfully refreshed from Google Patents.
US3846445A
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US
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Dibenzofuranyloxy and carbazolyloyx alkanoic acids and esters
Assignee: Astra Lakemedel AB
•
Filing: 1972-09-25
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Granted: 1974-11-05
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Expires: 1992-09-25
Abstract
Abstract Compounds of the general formula AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, WHEREIN X is -Oor -NH-; RO is H, F, Cl, Br or OCH3; R1 and R2 are the same or different and selected from the group consisting of H and alkyl groups having 1-3 carbon atoms; R3 is H or an alkyl group having 1-3 carbon atoms; Ro and the side-chain containing the radicals R1, R2 and R3 being placed on the same or different benzene ring. Pharmaceutical preparations containing these compounds are useful in a method for lowering the serum lipid concentration in mammals, including man. These same preparations are also useful for the combined lowering of serum cholesterol and triglyceride concentrations.
Inventors
- 👤 U Bondesson
- 👤 L Carlson
- 👤 C Hedbom
- 👤 H Magnusson
- 👤 N Stjernstrom
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 06:52
CPC Classifications
C; C07; C07D; C07D307/00; C07D307/77; C07D307/91; C07D209/00; C07D209/56; C07D209/80; C07D209/82; C07D209/88
Claims Analysis
Total Claims: 41
Claim 1
Independent Claim
12 words
A COMPOUND SELECTED FROM THE GROUP CONSISTING OF COMPOUNDS OF THE FORMULA
Claim 2
Dependent Claim
12 words
A COMPOUND SELECTED FROM THE GROUP CONSISTING OF COMPOUNDS OF THE FORMULA
Claim 3
Dependent Claim
34 words
A compound according to claim 1, in which formula X is -O- or -NH-; R0 represents H, R1 and R2 are CH3 and R3 is selected from the group consisting of H and C2H5.
Claim 4
Dependent Claim
32 words
A compound according to claim 1, in which formula X represents -O-; R0 represents H, R1 and R2 are CH3 and R3 is selected from the group consisting of H and C2H5.
Claim 5
Dependent Claim
15 words
A compound selected from the group consisting of 2-(4-Dibenzofuranyloxy)-2-methylpropionic acid and pharmaceutically acceptable salts thereof.
Claim 6
Dependent Claim
15 words
A compound selected from the group consisting of 2-(4-Dibenzofuranyloxy)-2-methylpropionic acid and pharmaceutically acceptable salts thereof.
Claim 7
Dependent Claim
1 words
Ethyl-2-(4-dibenzofuranyloxy)-2-methylpropionate.
Claim 8
Dependent Claim
1 words
Ethyl-2-(4-dibenzofuranyloxy)-2-methylpropionate.
Claim 9
Dependent Claim
15 words
A compound selected from the group consisting of 2-(3-Dibenzofuranyloxy)-2-methylpropionic acid and pharmaceutically acceptable salts thereof.
Claim 10
Dependent Claim
15 words
A compound selected from the group consisting of 2-(3-Dibenzofuranyloxy)-2-methylpropionic acid and pharmaceutically acceptable salts thereof.
Claim 11
Dependent Claim
1 words
Ethyl-2-(3-dibenzofuranyloxy)-2-methylpropionate.
Claim 12
Dependent Claim
1 words
Ethyl-2-(3-dibenzofuranyloxy)-2-methylpropionate.
Claim 13
Dependent Claim
15 words
A compound selected from the group consisting of 2-(2-Dibenzofuranyloxy)-2-methylpropionic acid and pharmaceutically acceptable salts thereof.
Claim 14
Dependent Claim
15 words
A compound selected from the group consisting of 2-(2-Dibenzofuranyloxy)-2-methylpropionic acid and pharmaceutically acceptable salts thereof.
Claim 15
Dependent Claim
1 words
Ethyl-2-(2-dibenzofuranyloxy)-2-methylpropionate.
Claim 16
Dependent Claim
1 words
Ethyl-2-(2-dibenzofuranyloxy)-2-methylpropionate.
Claim 17
Dependent Claim
15 words
A compound selected from the group consisting of 2-(1-Dibenzofuranyloxy)-2-methylpropionic acid and pharmaceutically acceptable salts thereof.
Claim 18
Dependent Claim
15 words
A compound selected from the group consisting of 2-(1-Dibenzofuranyloxy)-2-methylpropionic acid and pharmaceutically acceptable salts thereof.
Claim 19
Dependent Claim
1 words
Ethyl-2-(1-dibenzofuranyloxy)-2-methylpropionate.
Claim 20
Dependent Claim
1 words
Ethyl-2-(1-dibenzofuranyloxy)-2-methylpropionate.
Claim 21
Dependent Claim
15 words
A compound selected from the group consisting of 2-(2-Carbazolyloxy)-2-methylpropionic acid and pharmaceutically acceptable salts thereof.
Claim 22
Dependent Claim
15 words
A compound selected from the group consisting of 2-(2-Carbazolyloxy)-2-methylpropionic acid and pharmaceutically acceptable salts thereof.
Claim 23
Dependent Claim
14 words
A compound selected from the group consisting of Ethyl-2-(2-carbazolyloxy)-2-methylpropionate and pharmaceutically acceptable salts thereof.
Claim 24
Dependent Claim
14 words
A compound selected from the group consisting of Ethyl-2-(2-carbazolyloxy)-2-methylpropionate and pharmaceutically acceptable salts thereof.
Claim 25
Dependent Claim
15 words
A compound selected from the group consisting of 2-(6-Methoxy-4-dibenzofuranyloxy)-2-methylpropionic acid and pharmaceutically acceptable salts thereof.
Claim 26
Dependent Claim
15 words
A compound selected from the group consisting of 2-(6-Methoxy-4-dibenzofuranyloxy)-2-methylpropionic acid and pharmaceutically acceptable salts thereof.
Claim 27
Dependent Claim
1 words
Ethyl-2-(6-methoxy-4-dibenzofuranyloxy)-2-methylpropionate.
Claim 28
Dependent Claim
1 words
Ethyl-2-(6-methoxy-4-dibenzofuranyloxy)-2-methylpropionate.
Claim 29
Dependent Claim
15 words
A compound selected from the group consisting of 2-(1-Chloro-4-dibenzofuranyloxy)-2-methylpropionic acid and pharmaceutically acceptable salts thereof.
Claim 30
Dependent Claim
15 words
A compound selected from the group consisting of 2-(1-Chloro-4-dibenzofuranyloxy)-2-methylpropionic acid and pharmaceutically acceptable salts thereof.
Claim 31
Dependent Claim
1 words
Ethyl-2-(1-chloro-4-dibenzofuranyloxy)-2-methylpropionate.
Claim 32
Dependent Claim
1 words
Ethyl-2-(1-chloro-4-dibenzofuranyloxy)-2-methylpropionate.
Claim 33
Dependent Claim
15 words
A compound selected from the group consisting of 4-Dibenzofuranyloxyacetic acid and pharmaceutically acceptable salts thereof.
Claim 34
Dependent Claim
15 words
A compound selected from the group consisting of 4-Dibenzofuranyloxyacetic acid and pharmaceutically acceptable salts thereof.
Claim 35
Dependent Claim
1 words
Ethyl-4-dibenzofuranyloxyacetate.
Claim 36
Dependent Claim
1 words
Ethyl-4-dibenzofuranyloxyacetate.
Claim 37
Dependent Claim
15 words
A compound selected from the group consisting of 2-(4-dibenzofuranyloxy)-propionic acid and pharmaceutically acceptable salts thereof.
Claim 38
Dependent Claim
15 words
A compound selected from the group consisting of 2-(4-dibenzofuranyloxy)-propionic acid and pharmaceutically acceptable salts thereof.
Claim 39
Dependent Claim
1 words
Ethyl-2-(4-dibenzofuranyloxy)-propionate.
Claim 40
Dependent Claim
1 words
Ethyl-2-(4-dibenzofuranyloxy)-propionate.
Claim 41
Dependent Claim
14 words
A compound according to claim 1 in the form of an optically pure isomer.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1977-11-04 | 1978-05-06 | 1978-11-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1981-11-04 | 1982-05-06 | 1982-11-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1985-11-04 | 1986-05-06 | 1986-11-05 | $7700.00 | Window Closed / Lapsed |