US3843796A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Antihypertensive agents
Assignee: Merck and Co Inc
•
Filing: 1971-04-26
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Granted: 1974-10-22
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Expires: 1991-04-26
Abstract
Abstract N-( Alpha -Aminoacyl)- and N-( Alpha -acylaminoacyl) derivatives of Alpha -(1-aminoethyl)-m-hydroxybenzyl alcohol and Alpha -(1aminoethyl)-m-benzyloxybenzyl alcohol are disclosed and the processes for preparing such novel compounds are described. These compounds are used as antihypertensive agents.
Inventors
- 👤 C Miller
- 👤 R Miller
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 14:32
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/185; A61K31/19; A61K31/195
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
26 words
THE METHOD OF TREATING HYPERTENSION IN A HUMAN WHICH COMPRISES THE ADMINISTRATION TO A HYPERTENSIVE HUMAN OF A HYPOTENSIVE AMOUNT OF A COMPOUND OF THE FORMULA
Claim 2
Independent Claim
26 words
THE METHOD OF TREATING HYPERTENSION IN A HUMAN WHICH COMPRISES THE ADMINISTRATION TO A HYPERTENSIVE HUMAN OF A HYPOTENSIVE AMOUNT OF A COMPOUND OF THE FORMULA
Claim 3
Dependent Claim
23 words
The method according to claim 1 in which the parent Alpha -(1-aminoethyl)-m-hydroxybenzyl alcohol is of the ( + or - ) erythro configuration.
Claim 4
Dependent Claim
19 words
The method according to claim 1 in which the parent Alpha -(1-aminoethyl)-m-hydroxybenzyl alcohol is of the (-) erythro configuration.
Claim 5
Dependent Claim
47 words
The pharmaceutical preparation in dosage unit form adapted for administration to obtain relief from hypertension comprising per dosage unit, a pharmaceutical acceptable excipient and an effective hypotensive non-toxic amount within the range of from about 1 to 100 mg. of at least one compound of the formula
Claim 6
Dependent Claim
47 words
The pharmaceutical preparation in dosage unit form adapted for administration to obtain relief from hypertension comprising per dosage unit, a pharmaceutical acceptable excipient and an effective hypotensive non-toxic amount within the range of from about 1 to 100 mg. of at least one compound of the formula
Claim 7
Dependent Claim
19 words
The pharmaceutical preparation according to claim 4 in which the parent Alpha -(1-aminoethyl)-m-hydroxybenzyl alcohol is of the erythro configuration.
Claim 8
Dependent Claim
24 words
The pharmaceutical preparation according to claim 4 in which the percent Alpha -(1-aminoethyl)-m-hydroxybenzyl alcohol is of the (-) erythro or ( Alpha R,1S) configuration.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1977-10-21 | 1978-04-22 | 1978-10-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1981-10-21 | 1982-04-22 | 1982-10-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1985-10-21 | 1986-04-22 | 1986-10-22 | $7700.00 | Window Closed / Lapsed |