Preparation of aminocarboxylic acids from aminoalcohols

Abstract

Abstract 1.AN AQUEOUS PROCESS FOR PREPARING AMINOCARBOXYLIC ACID SALTS COMPRISING THE STEPS OF HEATING AN AMINOALCOHOL IN THE PRESENCE OF AT LEAST A STOICHIOMETRIC QUANTITY, BASED UPON THE AMINOALCOHOL EMPLOYED, OF SODIUM HYDROXIDE, CADMIUM SALTS, AND SUFFICIENT WATER TO MAINTAIN THE COMPONENTS IN THE REACTION MEDIUM IN SOLUTION, SAID AMINOALCOHOL BEING REPRESENTED BY THE FOLLOWING FORMULA: R"-N(-R'')-CH2-CH2-OH WHEREIN R'' REPRESENTS HYDROGEN OR A GROUP SELECTED FROM -CH2CH2OH, A C1 TO C15 ALKYL, OR AN AMINOALKYL GROUP HAVING TWO TO THREE CARBON ATOMS; AND R" REPRESENTS HYDROGEN OR A GROUP SELECTED FROM PHENYL, A C1 TO C15 ALKYL SUBSTITUTED PHENYL, OR C1 TO C15 ALKYL; AND WHEREIN EACH R'' AND R" CAN ALSO REPRESENT METHYLENE GROUPS, OR LOWER C1 TO C3 ALKYL SUBSTITUTED METHYLENE GROUPS, SUCH THAT WHEN TAKEN WITH N-CH2CH2OH THEY COMPRISES A PORTION OF AN N-SUBSTITUTED PIPERAZINE COMPOUND WHICH COMPOUND CAN BE FURTHER REPRESENTED BY THE FOLLOWING FORMULA: R"''-N<(-CH2-R"-N(-CH2-CH2-OH)-R''-CH2-) WHEREIN R"'' REPRESENTS HYDROGEN, OR A GROUP SELECTED FROM A C1 TO C4 ALKYL OR -CH2CH2OH;AND WHEREIN SAID HEATING 250*C. TO 300*C. FOR A TIME IN THE RANGE OF ABOUT ABOUT 250*C. TO 300*C. FOR A TIME IN THE RANGE OF ABOUT 5 TO 45 MINUTES UNDER A PRESSURE SUFFICIENT TO MAINTAIN THE WATER IN LIQUID PHASE.

Inventors

• 👤 H Schulze
• 👤 E Marquis

Bibliographic Details