3-cyano-2-pyrryl oxamic acids
Abstract
Abstract THIS INVENTION RELATES TO NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS OF THE FORMULA: 1-R3,2-(MO-CO-CO-NH-),3-(NC-),4-R1,5-R2-PYRROLE WHEREIN M IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, ALUMINUM, AMMONIUM, SODIUM, POTASSIUM, CALCIUM, AND TRIS-(HYDROXYMETHYL)METHYLAMMONIUM, R1 IS SELECTED FROM THE GROUP CONSISTING OF LOWER ALKYL OF 1 THROUGH 6 CARBON ATOMS, X-PHENYL WHEREIN X IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, FLUORINE, CHLORINE, BROMINE, METHOXY, METHYL AND TRIFLUOROMETHYL, R2 IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN AND LOWER ALKYL OF 1 THROUGH 6 CARBON ATOMS, AND R3 HAS THE SAME MEANING AS R1 AND IN ADDITION HYDROGEN. THE COMPOUNDS (1A) ABOVE ARE FORMULATED WITH PHARMACEUTICAL CARRIERS FOR INHALATION OR FOR ORAL, PARENTERAL OR RECTAL ADMINISTRATION, WITH INSUFFLATION BEING THE PREFERRED METHOD. THE COMPOSITONS ARE USEFUL IN THE PROPHYLACTIC TREATMENT OF SENSITIZED HUMANS AND MAMMALS FOR ALLERGIC AND ALL ANAPHYLACTIC REACTIONS OF A REAGIN-MEDIATED AND NON-REAGIN-MEDIATED NATURE.
Inventors
- 👤 H Johnson
- 👤 J Wright
- 👤 C Hall
- 👤 D Warner
Bibliographic Details
Claims Analysis
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