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US3835149A Expired / Lapsed US ⏱️ 0.0 years remaining

3-aroyl-alkenyleneimines

Assignee: Novartis Corp
•
Filing: 1972-07-07
•
Granted: 1974-09-10
•
Expires: 1992-07-07
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Abstract

Abstract 3-Aroyl-lower alkenyleneimines, e.g. those of the formula R H, alkyl, free, etherified or esterified OH, CF3 or an amino R'' H, alkyl or acyl M 1 OR 2 N 2-4 OR CARBONYL OR AMINO DERIVATIVES THEREOF ARE ANTI-INFLAMMATORY AGENTS.

Inventors

  • 👤 H Renfroe

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 16:34
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; C; C07; C07C; C07C255/00; C07D; C07D205/00; C07D205/02; C07D205/06; C07D207/00; C07D207/02; C07D207/18; C07D207/20; C07D211/00; C07D211/02; C07D211/04; C07D211/68; C07D211/70; C07D213/00; C07D213/02; C07D213/04; C07D213/24; C07D213/44; C07D213/46; C07D213/50

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 88 words
A compound as claimed in claim 1, in which formula Ar is phenyl, (lower alkyl)m-phenyl, (hydroxy)m-phenyl, (lower alkoxy)m-phenyl, (lower alkanoyloxy)m-phenyl, (halogeno)m-phenyl, (trifluoromethyl)m-phenyl, (amino)m-phenyl, (di-lower alkylamino)m-phenyl, (lower alkyl or trifluoromethyl)-halophenyl, m is the integer 1 or 2, the alkylene group CnH2n separates the carbon from the nitrogen atom by 2-4 carbon atoms, n is an integer from 2 to 7, R is hydrogen or lower alkyl, and R'' is hydrogen or lower alkanoyl, lower alkoxy-carbonyl, phenyl-carbamoyl or -thiocarbamoyl or a therapeutically useful acid addition salt of the amino compounds.
Claim 2
Dependent Claim 12 words
A compound as claimed in claim 1, and corresponding to the formula
Claim 3
Dependent Claim 35 words
A compound as claimed in claim 3, in which formula R is hydrogen, fluoro or chloro in the meta- or para-position, R'''' is hydrogen and m is the integer 1 and n the integer 3.
Claim 4
Dependent Claim 12 words
A compound as claimed in claim 3 and being the 3-benzoyl-1,4, 5,6-tetrahydropyridine.
Claim 5
Dependent Claim 13 words
A compound as claimed in claim 3 and being the 3-(3-fluoro or chlorobenzoyl)-1,4,5,6-tetrahydropyridine.

References Cited (Backward Citations)

US3489769A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1977-09-09 1978-03-11 1978-09-10 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1981-09-09 1982-03-11 1982-09-10 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1985-09-09 1986-03-11 1986-09-10 $7700.00 Window Closed / Lapsed

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