Novel pyrazolidone derivatives in pharmaceutical compositions and methods
Abstract
Abstract DIPHENYLPYRAZOLIDONE DERIVATIVES, SUBSTITUTED ON THE 4 POSITION AND HAVING THE FORMULA: 1,2-DIPHENYL,4-R,4-(CH3-(CH2)3-)-PYRAZOLIDINE-3,5-DIONE WHEREIN R IS SELECTED FROM THE GROUP CONSISTING OF GLYCOSES OF FROM 3 THROUGH 6 CARBONS IN CHAIN LENGTH, POLYOXYETHYLENE HAVING A MOLECULAR WEIGHT OF FROM 200 THROUGH 2000 AND AN IONIC EXCHANGE RESIN WHICH IS A POLYMERIC CONDENSATION PRODUCT OF A PHENOL, FORMALDEHYDE AND AN ALKYLENE POLYAMINE WHIC ARE KNOWN IN THE TRADE AS AMBERLITE RESINS, AND HYDROGEN BONDED COMPOUNDS OF THE STRUCTURE: 1,2-DIPHENYL,3-(O=),4-(CH3-(CH2)3-),4,5-(-Z-O-)PYRAZOLIDINE WHEREIN Z IS A COMPOUND OF THE GROUP SELECTED FROM ALGIN, GUM GUAR, PECTIN, PSYLLIUM, DEXTRAN AND POLYVINYLPYRROLIDONE AND THE METHODS FOR THE PREPARATION OF THE AFORESAID COMPOUNDS. THE COMPOUNDS ARE USEFUL IN ACHIEVING AN ANTI-INFLAMMATORY EFFECT.
Inventors
- 👤 G Negrevergne
Bibliographic Details
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