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US3829579A Expired / Lapsed US ⏱️ 0.0 years remaining

Stable solutions of pge-type compounds

Assignee: Pharmacia and Upjohn Co
•
Filing: 1973-05-11
•
Granted: 1974-08-13
•
Expires: 1993-05-11
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Abstract

Abstract Stable solutions of PGE-type compounds are obtained by dissolving the compounds in an anhydrous, water-miscible, pharmacologically acceptable, dipolar aprotic solvent.

Inventors

  • 👤 R Stehle
  • 👤 T Oesterling

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-30 17:59
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/557; A61K47/00; A61K47/06; A61K47/16; A61K47/18; A61K9/00; A61K9/0012; A61K9/0019; C; C07; C07C; C07C405/00

Claims Analysis

Total Claims: 15
Claim 1
Independent Claim 9 words
A solution according to claim 1 which is sterile.
Claim 2
Dependent Claim 22 words
A solution of a prostaglandin-like compound of the PGE-type in anhydrous N,N-dimethylacetamide in a concentration of at least 1 mg. per ml.
Claim 3
Dependent Claim 9 words
A solution according to claim 3 which is sterile.
Claim 4
Dependent Claim 15 words
A solution according to claim 3 wherein said compound is PGE1 or PGE1 methyl ester.
Claim 5
Dependent Claim 15 words
A solution according to claim 3 wherein said compound is 15-methyl-PGE1 or 15-methyl-PGE1 methyl ester.
Claim 6
Dependent Claim 15 words
A solution according to claim 3 wherein said compound is 15-methyl-PGE2 or 15-methyl-PGE2 methyl ester.
Claim 7
Dependent Claim 19 words
A solution according to claim 3 wherein said compound is 15 Beta -15-methyl-PGE1 or 15 Beta -15-methyl-PGE1 methyl ester.
Claim 8
Dependent Claim 19 words
A solution according to claim 3 wherein said compound is 15 Beta -15-methyl-PGE2 or 15 Beta -15-methyl-PGE2 methyl ester.
Claim 9
Dependent Claim 16 words
A solution according to claim 3 wherein said compound is 16, 16-dimethyl-PGE1 or 16,16-dimethyl-PGE1 methyl ester.
Claim 10
Dependent Claim 16 words
A solution according to claim 3 wherein said compound is 16, 16-dimethyl-PGE2 or 16,16-dimethyl-PGE2 methyl ester.
Claim 11
Dependent Claim 15 words
A solution according to claim 3 wherein said compound is 17-phenyl-18,19,20-trinor-PGE2 or 17-phenyl-18,19,20-trinor-PGE2 methyl ester.
Claim 12
Dependent Claim 23 words
A solution of PGE2 in an anhydrous, water-miscible, pharmacologically acceptable, dipolar aprotic solvent in a concentration of at least 1 mg. per ml.
Claim 13
Dependent Claim 13 words
A solution according to claim 13 in which the solvent is anhydrous N,N-dimethylacetamide.
Claim 14
Dependent Claim 17 words
A solution according to claim 14 in which said N,N-dimethylacetamide contains not more than 0.1 percent water.
Claim 15
Dependent Claim 9 words
A solution according to claim 15 which is sterile.

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1977-08-12 1978-02-11 1978-08-13 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1981-08-12 1982-02-11 1982-08-13 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1985-08-12 1986-02-11 1986-08-13 $7700.00 Window Closed / Lapsed

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