Indirect hemagglutination test with simultaneous absorption of heterologous antibodies
Abstract
Abstract AN INDIRECT HEMAGGLUTINATION TEXT IS PROVIDED HEREIN WHEREBY AN ANTIGEN IS ADSORBED ONTO ERTHROCYTES OF ANIMAL ORIGIN AND AGGLUTINATION OF THE ANTIGEN-SENSITIZED ERTHROCYTES IS INDUCED BY THE REACTION OF AN ANTIBODY SPECIFIC TO THE ADSORBED ANTIGENS, SAID METHOD CHARACTERIZED IN THAT THE HETEROLOGOUS AGGLUTININS PRESENT IN THE SERUM TO BE TESTED AND WHICH MIGHT REACT WITH THE HOMOLOGOUS RED BLOOD CELLS USED AS THE ANTIGEN CARRIER ARE REMOVED BY USE OF A SOLUTION OF DECOMPOSED RED BLOOD-CELL MEMBRANES OF THE ANIMAL RED BLOOD CELLS. THE PRESENT INVENTION ALSO PROVIDES FOR A REAGENT COMPOSED ESSENTIALLY OF THE AFOREMENTIONED SOLUTION IN CONJUNCTION WITH THE ERTHROCYTES CONTAINING THE ANTIGENS ADSORBED THEREUPON.
Inventors
- 👤 K Fujita
Bibliographic Details
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