Tricyclic pharmacological agents,intermediates and methods of making
Abstract
Abstract 5-(3-SUBSTITUTED-PROP - 1 - ENYLIDENE) - AND 5-(3-SUBSTITUTED-PROP-1-YNYL)- DERIVATIVES OF 5H - DIBENZO(A,D)CYCLOHEPHEPTNES AND 10,11-DIHYDRO - 5H-DIBENZO(A,D)CYCLOHEPTENNES AND METHODS OF MAKING. THE PROCESS OOF PREPARING THE 5-(3''-SUBSTITUTED-PROP-1-ENYLIDENE)- DERIVATIES COMPRISES REACTION OF THE APPROPRIATE 5-(3-SUBSTITUTED-PROP-1YNYL)- DERIVATIVE WITH A SUITABLE BASE. THE 5- (3-AMINO SUBSTITUTED - PROP-1-ETHYLIDENE )-DERIVATIVES EXIHIBTIT ANTIHISAMINE ACTIVITY AND ARE FURTHER USEFUL IN THE TREATMENT OF, AND/OR PALLIATION OF, ABNORMAL CONDITIONS, OCCURING IN MAMMALA, RELATED TO THE CENTRAL NERVOUS SYSTEM. THE REMAINING COMPOUNDS HAVE UTILITY AS INTERMEDIATES FOR PHARMACLOLGIVOLOGICALLY ACTIVE COMPOUNDS.
Inventors
- 👤 M Marx
- 👤 J Edwards
Bibliographic Details
Claims Analysis
Total Claims: 0References Cited (Backward Citations)
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| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
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| 3.5 Years (Year 4) | 1977-08-05 | 1978-02-04 | 1978-08-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1981-08-05 | 1982-02-04 | 1982-08-06 | $3760.00 | Window Closed / Lapsed |
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