Novel pregnanoic acid derivatives
Abstract
Abstract PREGNANOIC ACID DERIVATIVES OF THE FORMULA 2-R1,3-(R2O-CO-CO-),3A-(H3C-),5-Z,5A-Y,6-(H3C-),6,7-(-A-B- CO-CH=),8-X-PERHYDRO-BENZ(E)INDENE WHEREIN X IS HYDROGEN,HALOGEN,ORMETHYL; Y IS HYDROGEN ORHALOGEN; Z IS HYDROXY OR HALOGEN HAVING AN ATOMIC WEIGHT NO GREATER THAN Y; R1 IS HYDROGEN OR METHYL; R2 IS HYDROGEN, ALKALI METAL OR SUBSTITUTED OR UNSUBSTITUTED HYDROCARBON OF 1-8 CARBON ATOMS WHICH IS UNSUBSTITUTED OR SUBSTITUTED BY HYDROXY, HALO, ALKOXY, CARBOXY, CARBALKOXY, AMINO, ALKYLAMINO, DIALKYLAMINO, NITRO OR SULFATO, WHEREIN ALKYL IN EACH INSTANCE CONTAINS 1-4 CARBON ATOMS; AND --A--B--IS--CH=CH--,--CCI=CH-- OR, WHEN AT LEAST ONE OF X, Y AND R1 IS OTHER THAN HYDROGEN, --CH2--CH2; PROCESS PRONOUNCED TOPICAL ANTI-INFLAMMATORY ACTIVITY.
Inventors
- 👤 H Laurent
- 👤 H Hofmeister
- 👤 E Gerhards
- 👤 R Wiechert
- 👤 K Prezewowsky
- 👤 K Kolb
- 👤 K Mengel
Bibliographic Details
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