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US3821375A Expired / Lapsed US ⏱️ 0.0 years remaining

Treatment of otitis of dogs and cats with chloramphenicol-squalane composition

Assignee: ALPER C
•
Filing: 1972-06-02
•
Granted: 1974-06-28
•
Expires: 1992-06-02
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Abstract

Abstract Treatment of otitis in dogs and cats with a suspension, in a hydrocarbon base, of dispersed chloramphenicol and prednisolone together with dissolved tetracaine and squalane.

Inventors

No inventors recorded.

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-01 15:52
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/16; A61K31/165; A61K31/56; A61K31/57

Claims Analysis

Total Claims: 13
Claim 1
Independent Claim 30 words
A process as in claim 1 in which the composition contains an effective amount of prednisolone as an antiinflammatory agent and an effective amount of tetracaine as a local anesthetic.
Claim 2
Dependent Claim 37 words
Process as in claim 2 in which said composition is a flowable droplet-forming suspension containing impalpable finely divided solid chloramphenicol and prednisolone in a liquid which is a uniform mixture of tetracaine, squalane and a hydrocarbon base.
Claim 3
Dependent Claim 35 words
Process as in claim 1 in which the composition contains about 0.3 to 1 percent chloramphenicol, about 0.1 to 0.3 percent prednisolone, about 0.3 to 1 percent tetracaine and about 10 to 30 percent squalane.
Claim 4
Dependent Claim 37 words
Process as in claim 1 in which said chloramphenicol is present as a dispersed impalpable finely divided solid in a petrolatum base containing squalane, the proportion of squalane being about 10 to 30 percent of the composition.
Claim 5
Dependent Claim 37 words
A composition for treating otitis in domestic animals containing an effective amount of chlorampheNicol and also containing squalane, the proportion of squalane being at least about 10 percent and sufficient to increase the effectiveness of the composition.
Claim 6
Dependent Claim 32 words
A composition as in claim 6 containing about 0.3 to 1 percent chloramphenicol, about 0.1 to 0.3 percent prednisolone, about 0.3 to 1 percent tetracaine and about 10 to 30 percent squalane.
Claim 7
Dependent Claim 11 words
A composition as in claim 7, in an aliphatic hydrocarbon base.
Claim 8
Dependent Claim 37 words
Composition as in claim 8 in which said composition is a flowable droplet-forming suspension containing impalpable finely divided solid chloramphenicol and prednisolone in a liquid which is a uniform mixture of tetracaine, squalane and a petrolatum base.
Claim 9
Dependent Claim 33 words
A composition as in claim 6 which contains an effective amount of prednisolone, hydrocortisone or prednisone as an antiinflammatory agent and an effective amount of tetracaine, lidocaine or benzocaine as a local anesthetic.
Claim 10
Dependent Claim 38 words
A composition as in claim 6 in which said chloramphenicol is present as a dispersed impalpable finely divided solid in a petrolatum base containing squalane, the proportion of squalane being about 10 to 30 percent of the composition.
Claim 11
Dependent Claim 10 words
A composition as in claim 10 containing prednisolone and tetracaine.
Claim 12
Dependent Claim 43 words
Process as in claim 2 in which said composition contains, per milliliter, 4.2. mg chloramphenicol, 1.7 mg prednisolone, 4.2 mg tetracaine, 0.21 ml squalane and 300 mg white petrolatum, the balance being liquid petrolatum, said composition being a suspension of impalpable solid particles.
Claim 13
Dependent Claim 41 words
Composition as in claim 12 said composition containing, per milliliter, 4.2 mg chloramphenicol, 1.7 mg prednisolone, 4.2 mg tetracaine, 0.21 ml squalane and 300 mg white petrolatum, the balance being liquid petrolatum, said composition being a suspension of impalpable solid particles.

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1977-06-27 1977-12-27 1978-06-28 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1981-06-27 1981-12-27 1982-06-28 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1985-06-27 1985-12-27 1986-06-28 $7700.00 Window Closed / Lapsed

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