US3818097A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method of inhibiting histamine activity with isothioureas
Assignee: Smith Kline & French Laboratories Ltd
•
Filing: 1973-03-22
•
Granted: 1974-06-18
•
Expires: 1993-03-22
Abstract
Abstract A method of inhibiting histamine activity by administering S(heterocyclic-alkyl) isothioureas.
Inventors
- 👤 J Black
- 👤 G Durant
- 👤 J Emmett
- 👤 C Ganellin
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 10:54
CPC Classifications
C; C07; C07D; C07D233/00; C07D233/54; C07D233/64; C07D249/00; C07D249/02; C07D249/04; C07D249/08; C07D309/00; C07D309/02; C07D309/08; C07D309/10; C07D309/12
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
22 words
A method according to claim 1 in which A taken together with the carbon and nitrogen atoms shown forms an imidazolyl ring.
Claim 2
Dependent Claim
11 words
A method according to claim 1 in which R3 is hydrogen.
Claim 3
Dependent Claim
18 words
A method according to claim 1 in which the compound is the dihydrobromide or dihydrochloride salt of S-(2-(4(5)-imidazolyl)ethyl)isothiourea.
Claim 4
Dependent Claim
13 words
A method according to claim 1 in which the compound is N,N''-dimethyl-S-(2-(4(5)-imidazolyl)ethyl)isothiourea dihydrobromide.
Claim 5
Dependent Claim
13 words
A method according To claim 1 in which the compound is S-(4-(4(5)-imidazolyl)butyl)isothiourea dihydrobromide.
Claim 6
Independent Claim
28 words
A method of inhibiting gastric acid secretion which comprises administering internally to an animal in an amount sufficient to inhibit gastric acid secretion a compound of the formula:
Claim 7
Dependent Claim
18 words
A method according to claim 7 in which the compound is the dihydrobromide or dihydrochloride salt of S-(2-(4(5)-imidazolyl)ethyl)isothiourea.
Claim 8
Dependent Claim
22 words
A method according to claim 7 in which A taken together with the carbon and nitrogen atoms shown forms an imidazolyl ring.
References Cited (Backward Citations)
US3558640A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1977-06-17 | 1977-12-17 | 1978-06-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1981-06-17 | 1981-12-17 | 1982-06-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1985-06-17 | 1985-12-17 | 1986-06-18 | $7700.00 | Window Closed / Lapsed |