Anaesthetic steroids
Abstract
Abstract AS AN ANEASTHETIC COMPOSITION FOR ANESTHETISING A SUBJECT BY PARENTERAL ADMINISTRATION, AN AQUEOUS SOLUTION OR SUSPENSION OF 3A-HYDROXY-5A-PREGNANE-11,20-DIONE AS PRINCIPAL ACTIVE INGREDIENT. IF THE COMPOSITION IS IN SOLUTION FORM IT WILL CONTAIN AT LEAST 1 MG./ML. OF THIS STEROID AND AT LEAST 1% BY WEIGHT (10 MG./ML.) OF A PARENTERALLY ACCEPTABLE NON-IONIC SURFACE ACTIVE AGENT HAVING AN HLB VALUE OF FROM 9-18 THE SOLUTION ALSO PREFERABLY CONTAINS TO INCREASE THE SOLUBILITY OF THE 3A-HYDROXY - 5A - PREGNANE - 11,20-DIONE, AT LEAST ONE STEROID OF THE FORMULA 3-HO,21-(R-O-)PREGNANE-11,20-DIONE WHEREIN R IS SELECTED FROM THE GROUP CONSISTING OF A LOWER ALKANOYL GROUP, A HEMISUCCINOYL GROUP AND A BENZOYL GROUP. IF THE COMPOSITION IS IN SUSPENSION FORM IT WILL CONTAIN 0.1-2.0% BY WEIGHT OF THE PRINCIPAL ACTIVE STEROID, FROM 0.5-5.0% BY WEIGHT OF A NON-IONIC SURFACE ACTIVE AGENT HAVING AN HLB VALUE OF AT LEAST 9, AND, DESIRABLY, FROM 0.1-10% BY WEIGHT OF A SUSPENDING AGENT. THE COMPOSITION MAY BE PRESENTED IN DOSAGE UNIT FORM IN A CONTAINER CONTAINING 10 MG.-300 MG. OF THE PRINCIPAL ACTIVE STEROID.
Inventors
- 👤 B Davis
- 👤 G Phillipps
Bibliographic Details
Claims Analysis
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1977-06-10 | 1977-12-10 | 1978-06-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1981-06-10 | 1981-12-10 | 1982-06-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1985-06-10 | 1985-12-10 | 1986-06-11 | $7700.00 | Window Closed / Lapsed |