7-(o-aminomethylphenyl-acetamido)-3-(3-hydroxypyridazin-6-ylthiomethyl)-3-cephem-4-carboxylic acid
Abstract
Abstract 7-(O-AMINOMEHYLPHENYLACETAMIDO) - 3 - (3-HYDROXYPYRIDAZIN-6 - YLTHIOMETHYL) - 3 - CEPHEN-4-CARBOXYLIC ACID AND ITS NONTOXIC PHARMACEUTICALLY ACCEPTABLE SALTS AND ESPECIALLY ITS DIMETHANESULFONATE DERIVATIVE ARE VAUABLE AS ANTIBACTERIAL AGENTS, AS NUTRITIONAL SUPPLEMENTS IN ANIMAL FEEDS AND AS THERAPEUTIC AGENTS IN POULTRY AND ANIMALS, INCLUDING MAN, AND ARE ESPECIALLY USEFUL IN THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY MANY GRAMPOSITIVE AND GRAM-NEGATIVE BACTERIA. 1-(O-AMINOMETHYLPHENYLACETAMIDO) - 3 = (3 - HYDROXY-PYRIDAZIN-6-YLTHIOMETHYL) - 3 - CEPHEM - 4-CARBOXYLIC ACID IS PREPARED FOR EXAMPLE, BY TREATMENT AT 0*C. WITH TRIFLUOROACETIC ACID OF THE CORRESPONDING COMPOUND IN WHICH THE FREE AMINO GROUP IS PROTECTED WITH A TERT.-BUTOXYCARBONYL GROUP.
Inventors
- 👤 T Naito
- 👤 J Okumura
Bibliographic Details
Claims Analysis
Total Claims: 0References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1977-05-27 | 1977-11-26 | 1978-05-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1981-05-27 | 1981-11-26 | 1982-05-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1985-05-27 | 1985-11-26 | 1986-05-28 | $7700.00 | Window Closed / Lapsed |