Lung scanning 99m technetium macroaggregate and method of preparation
Abstract
Abstract A LUNG SCANNING AGENT AND METHOD, THE AGENT COMPRISING A 99M TECHNETIUM **-SULFUR** COLLOID MACROAGGREGATE STABILIZED WITH A DIALDEHYDE. MORE SPECIFICALLY, THE COMPOSITION COMPRISES A 99M TCO4 SOLUTION OF THE DESIRED ACTIVITY TOGETHER WITH GELATIN, AN ACID, AND THIOSULFATES AND PERRHENATES OF THE METALS OF GROUP IA OF THE PERIODIC TABLE OF THE ELEMENTS. THE COMPOSITION IS HEATED TO PRODUCE THE DESIRED MACROAGGREGATE PARTICLES AND A DIALDEHYDE SUCH AS GLUTARALDEHYDE IS ADDED TO STABILIZE THE PARTICLES. A HIGH PRECENTAGE OF THE PARTICLES PRODUCED UPON INJECTION ARE INITIALLY DISTRIBUTED THROUGHOUT THE LUNGS AND UPON CLEARANCE DISTRIBUTE THEMSELVES THROUGHOUT THE RETICULOENDOTHELIAL SYSTEM.
Inventors
- 👤 V Ficken
- 👤 S Halpern
- 👤 L Miller
Bibliographic Details
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