US3801455A
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Method for producing citric acid
Assignee: Takeda Pharmaceutical Co Ltd
•
Filing: 1971-07-02
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Granted: 1974-04-02
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Expires: 1991-07-02
Abstract
Abstract This invention relates to a method for producing citric acid, which comprises incubating a yeast, a mold or a bacterium whose growth is inhibited by a citric acid-antimetabolite or a precursor thereof and which is capable of accumulating a significant amount of citric acid in a cultured medium,and then recovering citric acid thus accumulated from said medium.
Inventors
- 👤 T Suzuki
- 👤 H Fukuda
- 👤 Y Sumino
- 👤 S Akiyama
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 10:06
CPC Classifications
C; C12; C12P; C12P7/00; C12P7/40; C12P7/44; C12P7/48; Y; Y10; Y10S; Y10S435/00; Y10S435/8215; Y10S435/822; Y10S435/824; Y10S435/83; Y10S435/84; Y10S435/911; Y10S435/921; Y10S435/938
Claims Analysis
Total Claims: 25
Claim 1
Independent Claim
14 words
A method according to claim 1, wherein said microorganism is Candida lipolytica (ATCC 20320).
Claim 2
Dependent Claim
14 words
A method according to claim 1, wherein said microorganism is Candida lipolytica (ATCC 20324).
Claim 3
Dependent Claim
14 words
A method according to claim 1, wherein said microorganism is Pichia haplophila (ATCC 20321).
Claim 4
Dependent Claim
14 words
A method according to claim 1, wherein said microorganism is Debaryomyces sp. (ATCC 20322).
Claim 5
Dependent Claim
14 words
A method according to claim 1, wherein said microorganism is Brettanomyces claussenii (ATCC 20323).
Claim 6
Dependent Claim
14 words
A method according to claim 1, wherein said microorganism is Brevibacterium flavum (ATCC 21682).
Claim 7
Dependent Claim
14 words
A method according to claim 1, wherein said microorganism is Achromobater nueleoacedives (ATCC 21683).
Claim 8
Dependent Claim
14 words
A method according to claim 1, wherein said microorganism is Corynebacterium fascians (ATCC 21684).
Claim 9
Dependent Claim
14 words
A method according to claim 1, wherein said microorganism is Arthrobacter paraffineus (ATCC 21685).
Claim 10
Dependent Claim
14 words
A method according to claim 1 wherein said microorganism is Penicillium chermisinum (ATCC 20325).
Claim 11
Dependent Claim
15 words
A method according to claim 1, wherein the incubation temperature is between 20* and 35C.
Claim 12
Dependent Claim
15 words
A method according to claim 1, wherein the incubation pH is between 2 and 8.
Claim 13
Independent Claim
121 words
A method for producing citric acid which comprises inoculating both medium (A) containing a citric acid-antimetabolite or a precursor thereof selected from the class consisting of halogenocitric acid, halogenoacetic acid, halogenopyruvic acid, halogenooxalacetic acid and halogenosuccinic acid and medium (B) free from such an antimetabolite or a precursor with a microorganism of the genus Candida, Pichia, Debaryomyces, Brettanomyces, Brevibacterium, Corynebacterium, Arthrobacter, Achromobacter or Penicillium to select a strain whose growth is inhibited on the medium (A) but which grows well on the medium B; then incubating this particular strain in a medium to cause the same to accumulate citric acid in the medium containing neither said citric acid-antimethabolite nor precursor, and finally recovering the citric acid thus accumulated from said medium.
Claim 14
Dependent Claim
14 words
A method according to claim 14 wherein said microorganism is Candida lipolytica (ATCC 20320).
Claim 15
Dependent Claim
14 words
A method according to claim 14, wherein said microorganism is Candida lipolytica (ATCC 20324).
Claim 16
Dependent Claim
14 words
A method according to claim 14, wherein said microorganism is Pichia haplophila (ATCC 20321).
Claim 17
Dependent Claim
14 words
A method according to claim 14, wherein said microorganism is Debaryomyces sp. (ATCC 20322).
Claim 18
Dependent Claim
14 words
A method according to claim 14, wherein said microorganism is Brettanomyces claussenii (ATCC 20323).
Claim 19
Dependent Claim
14 words
A method according to claim 14, wherein said microorganism is Brevibacterium flavum (ATCC 21682).
Claim 20
Dependent Claim
14 words
A method according to claim 14 wherein said microorganism is Achromobacter nueleoacidives (ATCC 21683).
Claim 21
Dependent Claim
14 words
A method according to claim 14 wherein said microorganism is Corynebacterium fascians (ATCC 21684).
Claim 22
Dependent Claim
14 words
A method according to claim 14 wherein said microorganism is Arthrobacter paraffineus (ATCC 21685).
Claim 23
Dependent Claim
14 words
A method according to claim 14, wherein said microorganism is Penicillium chermisinum (ATCC 20325).
Claim 24
Dependent Claim
15 words
A method according to claim 14 wherein the incubation temperature is between 20* and 35*C.
Claim 25
Dependent Claim
15 words
A method according to claim 14, wherein the incubation pH is between 2 and 8.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1977-04-01 | 1977-10-01 | 1978-04-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1981-04-01 | 1981-10-01 | 1982-04-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1985-04-01 | 1985-10-01 | 1986-04-02 | $7700.00 | Window Closed / Lapsed |