US3786341A
Expired / Lapsed
US
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Magnetic resonance spectrometer employing stochastic resonance by a pseudorandom binary sequence and time-share modulation
Assignee: Varian Medical Systems Inc
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Filing: 1972-10-26
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Granted: 1974-01-15
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Expires: 1992-10-26
Abstract
Abstract A magnetic resonance spectrometer employing a pseudorandom binary sequence to simultaneously excite magnetic resonance of a plurality of resonance lines in the spectrum of a sample under analysis, the driving radio frequency field being applied to the sample in a train of pulses in each binary sequence, the timing or phase of the pulses being changed in a stochastic manner in the sequence, the composite noise excited resonance signal being detected in a receiver and sampled in a multitude of time displaced intervals in correlation with the binary sequence and stored in an accumulative manner in the associated channels of a memory of subsequent processing, read-out and display, the receiver being activated during the time intervals between the application of the radio frequency pulses to the sample.
Inventors
- 👤 W Anderson
- 👤 R Ernst
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 12:43
CPC Classifications
G; G01; G01R; G01R33/00; G01R33/20; G01R33/44; G01R33/46; G01R33/4616
Claims Analysis
Total Claims: 22
Claim 1
Independent Claim
205 words
A magnetic resonance spectrometer comprising transmitter means for producing a spectrum of radio frequency energy to be applied to the sample under analysis, said spectrum covering a plurality of separate magnetic resonance lines in the sample, to thereby produce simultaneous resonance of said lines within the sample, said transmitter means comprising a radio frequency generator for producing a driving radio frequency signal, and means for applying said radio frequency signal to said sample in the form of a plurality of repetitive trains of pulses, the trains of pulses being similar, the pulses in each train being stochastic, receiver means for detecting the simultaneously excited resonance lines of the sample to obtain a composite resonance signal, said receiver means including, means for time scanning and storing a multiplicity of successive time displaced values of the composite resonant signal in a multiplicity of associated memory channels, means for synchronizing the storage of the succes-sive time displaced resonance values in the respective channels with said repetitive trains of pulses, and means for reading out the signal values stored in said memory channels, and means synchronized with said transmitter means for activating said receiver means in the time intervals between said pulses of said train of radio frequency pulses.
Claim 2
Dependent Claim
205 words
A magnetic resonance spectrometer comprising transmitter means for producing a spectrum of radio frequency energy to be applied to the sample under analysis, said spectrum covering a plurality of separate magnetic resonance lines in the sample, to thereby produce simultaneous resonance of said lines within the sample, said transmitter means comprising a radio frequency generator for producing a driving radio frequency signal, and means for applying said radio frequency signal to said sample in the form of a plurality of repetitive trains of pulses, the trains of pulses being similar, the pulses in each train being stochastic, receiver means for detecting the simultaneously excited resonance lines of the sample to obtain a composite resonance signal, said receiver means including, means for time scanning and storing a multiplicity of successive time displaced values of the composite resonant signal in a multiplicity of associated memory channels, means for synchronizing the storage of the succes-sive time displaced resonance values in the respective channels with said repetitive trains of pulses, and means for reading out the signal values stored in said memory channels, and means synchronized with said transmitter means for activating said receiver means in the time intervals between said pulses of said train of radio frequency pulses.
Claim 3
Dependent Claim
55 words
A spectrometer as claimed in claim 1 wherein said means for applying said RF signal includes means for generating said train of pulses, said train of RF pulses comprising a plurality of pulses, each said pulse being spaced apart equally and the phase of said RF of said pulses being stochastically related to each other.
Claim 4
Dependent Claim
21 words
A spectrometer as claimed in claim 2 wherein said phase of said RF takes either of two predetermined values determined stochastically.
Claim 5
Dependent Claim
120 words
A spectrometer as claimed in claim 2 wherein said means for applying said pulses of radio frequency signal to said sample comprises a phase modulator for modulating the phase of said radio frequency signal of said radio frequency generator, a pseudorandom sequence generator for controlling said phase modulator to produce a pseudorandom phase switching of said radio frequency signal, a source of clock pulses for controlling said pseudorandom sequence generator, gating means for providing said pseudorandomly phase shifted radio frequency signal to said sample in the form of a plurality of repetitive trains of separate, spaced apart pulses, and a pulse generator means coupled to said source of clock pulses and to said gating means for controlling said gating means.
Claim 6
Dependent Claim
52 words
A spectrometer as claimed in claim 4 wherein said means synchronized with said transmitter means comprises a second gating means coupling the receiver means to the sample, and a second pulse generator means coupled to said second gating means and to said source of clock pulses for controlling said second gating means.
Claim 7
Dependent Claim
62 words
A spectrometer as claimed in claim 2 including means for providing a second radio frequency signal to said sample at a frequency different from the frequency of said first radio frequency signal and in the form of pulses, and means for synchronizing the application of said pulses of said second radio frequency signal with the pulses of said first radio frequency signal.
Claim 8
Dependent Claim
62 words
A spectrometer as claimed in claim 1 including means for providing a second radio frequency signal to said sample at a frequency different from the frequency of said first radio frequency signal and in the form of pulses, and means for synchronizing the application of said pulses of said second radio frequency signal witH the pulses of said first radio frequency signal.
Claim 9
Dependent Claim
29 words
A magnetic resonance spectrometer as claimed in claim 1 wherein said train of pulses comprises a plurality of pulses of equal width with stochastically varying time spacing between pulses.
Claim 10
Dependent Claim
81 words
A spectrometer as claimed in claim 8 wherein said means for applying said pulses of radio frequency signal to said sample comprises gating means coupling the output of said radio frequency generator to said sample, a pulse generator for controlling said gating means to gate said radio frequency signal to said sample, a pseudorandom sequence generator means coupled to said pulse generator for producing stochastic time spacing between pulses, and a source of clock pulses for controlling said pseudorandom sequence generator.
Claim 11
Dependent Claim
50 words
A spectrometer as claimed in claim 9 wherein said means synchronized with said transmitter means comprises a second gating means coupling the receiver means to the sample, and a second pulse generator for controlling said second gating means, said second pulse generator being coupled to said source of clock pulses.
Claim 12
Dependent Claim
62 words
A spectrometer as claimed in claim 8 including means for providing a second radio frequency signal to said sample at a frequency different from the frequency of said first radio frequency signal and in the form of pulses, and means for synchronizing the application of said pulses of said second radio frequency signal with the pulses of said first radio frequency signal.
Claim 13
Dependent Claim
21 words
A spectrometer as claimed in claim 1 wherein said train of pulses comprises a plurality of pulses with stochastically varying widths.
Claim 14
Dependent Claim
63 words
A spectrometer as claimed in claim 12 wherein said means for applying said pulses of radio frequency signal to said sample comprises gating means coupling the output of said radio frequency generator to said sample, a pseudorandom pulse generator coupled to said gating means for controlling operation of said gating means, and a source of clock pulses for controlling said pseudo-random pulse generator.
Claim 15
Dependent Claim
41 words
A spectrometer as claimed in claim 13 wherein said means synchronized with said transmitter means comprises a second gating means coupling the receiver means to the sample, said second gating means being coupled to and responsive to said pseudorandom pulse generator.
Claim 16
Dependent Claim
62 words
A spectrometer as claimed in claim 11 including means for providing a second radio frequency signal to said sample at a frequency different from the frequency of said first radio frequency signal and in the form of pulses, and means for synchronizing the application of said pulses of said second radio frequency signal with the pulses of said first radio frequency signal.
Claim 17
Independent Claim
203 words
The method for producing a magnetic resonance spectrum from a sample under analysis comprising the steps of producing a spectrum of radio frequency energy to be applied to the sample, said spectrum covering a plurality of separate magnetic resonance lines in the sample, to thereby produce simultaneous resonance of said lines within the sample, said spectrum producing step including producing a driving radio frequency signal and applying said radio frequency signal to said sample in the form of a plurality of repetitive trains of pulses, the trains of pulses being similar, the pulses in each train varying stochastically, detecting the simultaneously excited resonance lines of the sample to obtain a composite resonance signal, said detecting step including scanning and storing a multiplicity of successive time displaced components of the composite resonant signal in a multiplicity of associated memory channels, synchronizing the storage of the successive time displaced resonance components in the respective channels with said repetitive trains of pulses, and reading out the signal components stored in said memory channels, said detecting step further including synchronizing said applied radio frequency pulses with said resonance Detecting to perform said resonance detection in the time periods between pulses of said train of radio frequency pulses.
Claim 18
Independent Claim
203 words
The method for producing a magnetic resonance spectrum from a sample under analysis comprising the steps of producing a spectrum of radio frequency energy to be applied to the sample, said spectrum covering a plurality of separate magnetic resonance lines in the sample, to thereby produce simultaneous resonance of said lines within the sample, said spectrum producing step including producing a driving radio frequency signal and applying said radio frequency signal to said sample in the form of a plurality of repetitive trains of pulses, the trains of pulses being similar, the pulses in each train varying stochastically, detecting the simultaneously excited resonance lines of the sample to obtain a composite resonance signal, said detecting step including scanning and storing a multiplicity of successive time displaced components of the composite resonant signal in a multiplicity of associated memory channels, synchronizing the storage of the successive time displaced resonance components in the respective channels with said repetitive trains of pulses, and reading out the signal components stored in said memory channels, said detecting step further including synchronizing said applied radio frequency pulses with said resonance Detecting to perform said resonance detection in the time periods between pulses of said train of radio frequency pulses.
Claim 19
Dependent Claim
61 words
The method as claimed in claim 16 including the steps of providing a second radio frequency signal to said sample at a frequency different from the frequency of said first radio frequency signal and in the form of pulses, and synchronizing the application of said pulses of said second radio frequency signal with the pulses of said first radio frequency signal.
Claim 20
Dependent Claim
23 words
The method as claimed in claim 15 wherein said train of pulses comprises a plurality of equally spaced pulses with stochastically varying phase.
Claim 21
Dependent Claim
27 words
The method as claimed in claim 15 wherein said train of pulses comprises a plurality of pulses of equal width with stochastically varying time spacing between pulses.
Claim 22
Dependent Claim
21 words
The method as claimed in claim 15 wherein said train of pulses comprises a plurality of pulses with stochastically varying widths.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1977-01-14 | 1977-07-16 | 1978-01-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1981-01-14 | 1981-07-16 | 1982-01-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1985-01-14 | 1985-07-16 | 1986-01-15 | $7700.00 | Window Closed / Lapsed |