Chemical intermediates for the production of substituted 2-anilinophenylacetic acids and esters
Abstract
Abstract SUBSTITUTED 2-ANILINOPHENYLACETONITRILES, 2-ANILINOBENZYL ALCOHOLS AND 2-ANILINOPHENYLGLYOXYLIC ACIDS ARE VALUABLE CHEMICAL INTERMEDIATES FOR THE PREPARATION OF SUBSTITUTED 2-ANILINOPHENYLACETIC ACIDS AND ESTERS THEREOF. THE 2-ANILINOPHENYLACETIC ACIDS AND -PHENYL-ACETATES HAVE DESIRABLE ABSORPTION PATTERNS FOR PROTECTING THE SKIN AGAINST THE IRRITATING EFFECTS OF ULTRAVIOLET LIGHT AND ARE ALSO ANTI-INFLAMMATORY AGENTS. THE 2-ANILINOPHENYLACETONITRILES ARE OBTAINED FROM THE 2-ANILINOBENZYL ALCOHOLS THROUGH FORMATION OF THE INTERMEDIATE 2-ANILINOBENZYL CHLORIDES. THE 2-ANILINOBENZYL ALCOHOLS ARE OBTAINED FROM THE CORRESPONDING N-PHENYL ANTHRANILIC ACID. THE 2-ANILINOPHENYLGLYOXYLIC ACIDS ARE OBTAINED FROM N-PHENYLANILINES.
Inventors
- 👤 A Sallman
- 👤 R Pfister
Bibliographic Details
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