US3774103A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method of recording spin resonance spectra and a spin resonance spectrometer suited for the purpose
Assignee: Individual
•
Filing: 1971-07-21
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Granted: 1973-11-20
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Expires: 1991-07-21
Abstract
Abstract In recording spin resonance spectra, when the sample is excited by an RF-pulse in a homogeneous magnetic field for measurement and then all resonance frequencies of the sample are registered as an interferogram and evaluated, a pulse-excited magnetic field for measurement is used according to the invention. In this way, higher field strengths can be achieved for the magnetic field of measurement than has been possible before. These higher field strengths permit improved resolution of the fine structure of macromolecules. A spin resonance spectrometer suited for this method has an air-core coil for generation of the excited magnetic field and an energy source connected with the air-core coil which comprises devices for keeping constant the current flow in the coil for the duration of the respective pulse.
Inventors
- 👤 G Laukien
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 22:18
CPC Classifications
G; G01; G01R; G01R33/00; G01R33/20; G01R33/28; G01R33/38; G01R33/381; G01N; G01N24/00; G01R33/389; G01R33/44; G01R33/46
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
108 words
A method of recording spin resonance spectra, specifically, nuclear spin resonance spectra, comprising, introducing a sample into a polarizing magnetic field which is at least approximately homogeneous, subsequently exciting said sample with an RF-pulse, then simultaneously registering all resonance frequencies of the sample as an interferogram and, finally, subjecting the interferogram to a Fourier analysis, characterized by the further step of applying a magnetic field of measurement with pulse-type excitation to said sample at the termination of excitation of the sample by said RF-pulse, the duration of which is essentially equal to the sum of the duration of the RF-pulse and the relaxation time of the excited spins.
Claim 2
Independent Claim
108 words
A method of recording spin resonance spectra, specifically, nuclear spin resonance spectra, comprising, introducing a sample into a polarizing magnetic field which is at least approximately homogeneous, subsequently exciting said sample with an RF-pulse, then simultaneously registering all resonance frequencies of the sample as an interferogram and, finally, subjecting the interferogram to a Fourier analysis, characterized by the further step of applying a magnetic field of measurement with pulse-type excitation to said sample at the termination of excitation of the sample by said RF-pulse, the duration of which is essentially equal to the sum of the duration of the RF-pulse and the relaxation time of the excited spins.
Claim 3
Dependent Claim
43 words
A method as claimed in claim 1, characterized in that said polarizing magnetic field to which the sample is exposed is a continuous magnetic field of polarization of lower field strength in the intervals between the pulses of the magnetic field of measurement.
Claim 4
Dependent Claim
34 words
A method as claim in claim 2, characterized in that the sample is transferred from the area of the continuous magnetic field of polarization into the area of the pulsed magnetic field of measurement.
Claim 5
Dependent Claim
58 words
A method as claimed in claim 2, characterized in that the sample is exposed in the same place alternately to the continuous magnetic field of polarization and the pulsed field of measurement and the magnetic field of measurement is generated by superposition of the magnetic field of polarization by a pulsed magnetic field acting in the same direction.
Claim 6
Dependent Claim
26 words
A method as claimed in claim 2, characterized in that the sample is excited by the RF-pulse immediately before the pulsed magnetic field is turned on.
Claim 7
Dependent Claim
56 words
A method as claimed in claim 1, characterized in that the interferogram recorded is transformed into a lower frequency range by superposition with a reference frequency prior to performance of the Fourier analysis and the magnitude of This reference frequency is controlled as a function of the instantaneous field strength of the mangetic field of measurement.
Claim 8
Dependent Claim
55 words
A method as claimed in claim 6, characterized in that the reference frequency is controlled as a function of the field strength of the magnetic field of measurement in the way known from magnetic field stabilization as a function of the resonance frequency of standard samples which are exposed to the magnetic field of measurement.
Claim 9
Dependent Claim
142 words
A spin resonance spectrometer, specifically a nuclear spin resonance spectrometer, comprising generating means for generation of at least an approximately homogneous magnetic measuring field, means for introducing samples into this magnetic measuring field, means for excitation of samples with a pulsed RF-field, means for detecting the spin resonances excited in the sample, and means for registration and evaluation of the resonance frequencies of the detected spin resonances by Fourier analysis characterized in that said generating means includes an energy source supplying current pulses of high current intensity and an air-core coil for generation of an excited pulsed magnetic field aligned with said measuring field, which coil is connected to said energy source, and means for maintaining constant the current flow in the coil and thus the magnetic field generated by the coil for a considerable part of the duration of the pulse.
Claim 10
Dependent Claim
142 words
A spin resonance spectrometer, specifically a nuclear spin resonance spectrometer, comprising generating means for generation of at least an approximately homogneous magnetic measuring field, means for introducing samples into this magnetic measuring field, means for excitation of samples with a pulsed RF-field, means for detecting the spin resonances excited in the sample, and means for registration and evaluation of the resonance frequencies of the detected spin resonances by Fourier analysis characterized in that said generating means includes an energy source supplying current pulses of high current intensity and an air-core coil for generation of an excited pulsed magnetic field aligned with said measuring field, which coil is connected to said energy source, and means for maintaining constant the current flow in the coil and thus the magnetic field generated by the coil for a considerable part of the duration of the pulse.
Claim 11
Dependent Claim
36 words
A spin resonance spectrometer as claimed in claim 8, characterized in that the means for keeping constant the current flow comprise several current sources, and including means for selectively connecting said current sources to said coil.
Claim 12
Dependent Claim
32 words
A spin resonance spectrometer as claimed in claim 9, characterized in that the energy source is designed as a capacitor bank whose capacitors forming the partial sources are charged to different voltages.
Claim 13
Dependent Claim
27 words
A spin resonance spectrometer as claimed in claim 8, characterized in that the means for keeping constant the current flow contain impedances that may be selectively disconnected.
Claim 14
Dependent Claim
34 words
A spin resonance spectrometer as claimed in claim 8, characterized in that the means for keeping constant the current flow contain control stages equipped with active circuit elements for control of the current intensity.
Claim 15
Dependent Claim
34 words
A spin resonance spectrometer as claimed in claim 8, characterized in that the means for keeping constant the current flow comprise a control unit responding to the field strength of the pulsed magnetic field.
Claim 16
Dependent Claim
23 words
A spin resonance spectrometer as claimed in claim 8, characterized in that the air-core coil is arranged in the gap of a ferromagnet.
Claim 17
Dependent Claim
24 words
A spin resonance spectrometer as claimed in claim 8, characterized in that the air-core coil is arranged in the magnetic field of a cryomagnet.
Claim 18
Dependent Claim
97 words
A spin resonance spectrometer as claimed in claim 8, characterized in that the device for registration and evaluation of the resonance frequencies comprises a generator for a reference frequency which is controlled by a resonance frequency of a standard sample contained in the magnetic field of measurement in such a way that the reference frequency is in a certain relation to the resonance frequency of the standard sample, and a superposition device in the form of a phase detector, in which the resonance frequencies recorded are superimposed the reference frequency for transformation into a lower frequency range.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1976-11-19 | 1977-05-21 | 1977-11-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1980-11-19 | 1981-05-21 | 1981-11-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1984-11-19 | 1985-05-21 | 1985-11-20 | $7700.00 | Window Closed / Lapsed |