X-ray contrast agents
Abstract
Abstract THE INVENTION PROVIDES X-RAY CONTRAST AGENTS AND COMPOSITIONS CONTAINING THEM. THE NEW AGENTS OF THE INVENTION ARE COMPOUNDS OF THE FORMULA: (2,4,6-TRI(I-),3-(AC-N(-R1)-),5-(HOOC-)PHENYL)-N(-AC)-X- N(-AC)-(2,4,6-TRI(I-),5-(HOOC-)-1,3-PHENYLENE)-N(-AC)-R2 OR A SALT THEREOF WITH A PHYSIOLOGICALLY ACCEPTABLE ORGANIC OR INORGANIC BASE, WHEREIN R1 IS A HYDROGEN ATOM OR AN ALKYL GROUP CONTAINING UP TO THREE CARBON ATOMS WHICH MAY BE SUBSTITUTED BY ONE OR TWO HYDROXY GROUPS; R2 IS A HYDROGEN ATOM, AN ALKYL GROUP CONTAINING UP TO THREE CARBON ATOMS WHICH MAY BE SUBSTITUTED BY ONE OR TWO HYDROXY GROUPS, OR A GROUP OF THE FORMULA: (2,4,6-TRI(I-),3-(AC-N(-R1)-),5-(HOOC-)PHENYL)-N(-AC)-X- AC IS AN ACETYL OR PROPIONYL GROUP; AND X IS AN ALKYLENE GROUP CONTAINING FROM 3 TO 6 CARBON ATOMS.
Inventors
- 👤 T Ivar
- 👤 B Ekstrand
- 👤 A Munksgaard
- 👤 A Ronlan
- 👤 B Wickberg
Bibliographic Details
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