US3772153A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Apparatus for the preservation of animal or human organs in living condition
Assignee: Air Liquide SA
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Filing: 1971-02-25
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Granted: 1973-11-13
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Expires: 1991-02-25
Abstract
Abstract An apparatus for the preservation of living tissue such as an organ excised from the body for an extended time with a view toward future transplant thereof. The organ is placed in a refrigerated environment and under pressure while a nutrient fluid is circulated through its arterial complex. The gas utilized for pressurizing the environment of the organ is biochemically inert and serves as a carrier of oxygen which is absorbed by the nutrient, the latter being subjected to the influence of the pressurizing gas.
Inventors
- 👤 Roissart H De
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 05:38
CPC Classifications
A; A01; A01N; A01N1/00; A01N1/10; A01N1/12
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
56 words
Apparatus in accordance with claim 1, wherein one of said chambers is closed, a bypass means for interconnecting the closed chamber with said vessel, and an auxiliary conduit interconnecting said closed chamber with the second conduit means, said auxiliary conduit including means for indicating the pressure difference between said auxiliary conduit and said second conduit means.
Claim 2
Dependent Claim
120 words
Apparatus for keeping alive an organ of human or animal origin comprising, in combination, a sealed vessel adapted to contain said organ, a sealed nutrient fluid container, means for refrigerating the vessel and the container, a replenishing tank located above the nutrient fluid container, said replenishing tank having an outlet leading to said container, fluid transmitting means attached to said organ and forming a closed circuit with said container, means for circulating the nutrient fluid through said closed circuit, a source of gas under pressure, said gas comprising a mixture of inert gas and oxygen, first conduit means for introducing gas from said source into said container, and second conduit means for introducing gas from said source into said vessel.
Claim 3
Dependent Claim
172 words
Apparatus for preserving an organ comprising, in combination, a sealed vessel adapted to contain said organ, a sealed nutrient fluid container, means for refrigerating the vessel and the container, fluid transmitting means interconnecting said container and the organ within said vessel for supplying nutrient fluid to said organ and for returning the nutrient fluid to the container, a supply of gaseous fluid under pressure, said gaseous fluid including a biochemically inert gas and oxygen mixed therewith, the amount of oxygen mixed with said gas being under ten percent by volume, first conduit means interconnecting said supply and said Container for introducing gaseous fluid from said supply into said container, the gaseous fluid dissolving in said nutrient fluid within said container, second conduit means interconnecting said supply and said vessel for introducing gaseous fluid from said supply into said vessel, means for maintaining the pressure within said vessel in excess of the pressure in said container, and means for directing the nutrient fluid in said container through said transmitting means to said organ.
Claim 4
Dependent Claim
193 words
Apparatus for preserving an organ comprising, in combination, a sealed vessel adapted to contain said organ, said vessel having liquid level sensing means therein, a sealed nutrient fluid container, means for refrigerating the vessel and the container, fluid transmitting means interconnecting said container and the organ within said vessel for supplying nutrient fluid to said organ and for returning the nutrient fluid to the container, a supply of gaseous fluid under pressure, said gaseous fluid including a biochemically inert gas and oxygen mixed therewith, the amount of oxygen mixed with said gas being under ten percent by volume, first conduit means interconnecting said supply and said container for introducing gaseous fluid from said supply into said container, the gaseous fluid dissolving in said nutrient fluid within said container, second conduit means interconnecting said supply and said vessel for introducing gaseous fluid from said supply into said vessel, means for directing the nutrient fluid in said container through said transmitting means to said organ, and means controlled by said level sensing means and responsive to a predetermined increase in the liquid within said vessel for interrupting the flow of gaseous fluid into said container.
Claim 5
Dependent Claim
27 words
Apparatus in accordance with claim 5, in which the fluid transmitting means includes means for initiating the flow of nutrient fluid from said container to said organ.
References Cited (Backward Citations)
US3406531A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1976-11-12 | 1977-05-14 | 1977-11-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1980-11-12 | 1981-05-14 | 1981-11-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1984-11-12 | 1985-05-14 | 1985-11-13 | $7700.00 | Window Closed / Lapsed |