Method of preparing a killed vaccine for oral use
Abstract
Abstract A PROCESS FOR THE PROPAGATION OF RABIES VIRUS AND THE PRODUCTION THEREFROM OF A KILLED RABIES VACCINE WHICH IS SUBSTANTIALLY FREE FROM NON-HUMAN, NON-SPECIFIC PROTEIN IN WHICH THE VACCINE CONTAINS PROTEIN FROM THE GROUP CONSISTING OF FRACTION V OF HUMAN PLASMA AND THE MATERIAL OBTAINED FROM THE SUPERNATANT OBTAINED IN THE PRODUCTION OF FRACTION V BY CONCENTRATION, DIALYSIS AND FREEZE-DRYING OF SAID SUPERNATANT, THE NOMENCLATURE "FRACTION V" BEING THE NOMENCLATURE USED IN THT COHN COLD ETHANOL PROCESS FOR FRACTIONATION OF PLASMA. THE KILLED RABIES VACCINE MAY BE POTENTED BY ADJUVANTS TO ENHANCE IMMUNOGENIC PROPERTY. IN THE FOLLOWING DISCLOSURE, THE WORDS NON-SPECIFIC PROTEIN REFER TO ALL PROTEINS OTHER THAN T HE SPECIFIC PROTEIN WHICH IS RELATED TO THE CELL-ADAPTED RABIES VIRUS WHICH IS USED IN THE INOCULATION OF THE TISSUE CULTURE COMPOSITION OF CELLS.
Inventors
- 👤 P Fenje
Bibliographic Details
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1976-10-29 | 1977-04-30 | 1977-10-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1980-10-29 | 1981-04-30 | 1981-10-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1984-10-29 | 1985-04-30 | 1985-10-30 | $7700.00 | Window Closed / Lapsed |