N-substituted piperidine compounds

Abstract

Abstract N-SUBSTITUTED PIPERIDINE COMPOUNDS OF THE FORMULA: (2-Y2,5-X-PHENYL)-C(=CH-(CH2)2-N<(-(CH2)2-Z-(CH2)2-))- (1,2-PHENYLENE)-Y1 WHEREIN X IS A MEMBER SELECTED FROM THE GROUP CONSISTING OF H, CL, CH3, CF3, OCH3 AND SCH3, EACH OF Y1 AND Y2 IS H OR Y1 AND Y2 COMBINED MAY REPRESENT A MEMBER SELECTED FROM THE GROUP CONSISTING OF -CH2-CH2-, -CH=CH-, -C(CH3)2-, -O- AND -S-, OR THE CARBON ATOMS OF THE BENZENE RINGS TO WHICH Y1 AND Y2 ARE ATTACHED, MAY BE DIRECTLY COMBINED TO FORM A FLUORINE RING, AND Z IS >C(-N(-R1)2)-CO-NH2 IN WHICH -N(R1)2 IS A MEMBER SELECTED FROM THE GROUP CONSISTING OF DIMETHYLAMINO, PIPERIDINO AND >C<(-N(-R2)-CO-A-S-) IN WHICH A IS A MEMBER SELECTED FROM THE GROUP CONSISTING OF -CH2-, -CH2-CH2- AND -CH(CH3)- AND R2 IS A MEMBER SELECTED FROM THE GROUP CONSISTING OF H AND A LOWER ALKYL GROUP OF FROM 1 TO 2 CARBON ATOMS, AND THE METHOD OF PREPARING SAME. THESE COMPOUNDS ARE USEFUL AS PSYCHOTROPIC AGENTS.

Inventors

• 👤 M Nakanishi
• 👤 C Tashiro
• 👤 K Araki

Bibliographic Details