Patent US3713659A successfully refreshed from Google Patents.
US3766162A
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Barbituric acid antigens and antibodies specific therefor
Assignee: F Hoffmann La Roche AG
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Filing: 1971-08-24
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Granted: 1973-10-16
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Expires: 1991-08-24
Abstract
Abstract BARBITURIC ACID ANTIGENS ARE PREPARED BY COUPLING 5OR 5,5-SUBSTITUTED BARBITURIC ACID TO IMMUNOGENIC CARRIER MATERIALS. IN PREFERRED EMBODIMENTS, PROTEINS ARE USED AS THE CARRIER MATERIALS AND THE COUPLING IS EFFECTED BY AN AMIDE LINKAGE BETWEEN THE 5-SUBSTITUENT OF THE BARBITURIC ACID AND A CARBOXYL OR AMINO GROUP OF THE PROTEIN. THE RESULTING ANTIGENS PRODUCE IMMUNOLOGICAL EFFECTS WHEN INJECTED INTO HOST ANIMALS, INCLUDING THE FORMATION OF ANTIBODIES SPECIFIC FOR 5- AND 5,5-SUBSTITUTED BARBITURIC ACIDS. THESE SPECIFIC ANTIBODIES ARE USEFUL IN BIOANALYTICAL TECHNIQUES FOR THE ASSAY OF BARBITURIC ACIDS IN BIOLOGICAL FLUIDS.
Inventors
- 👤 S Spector
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 19:29
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/94; G01N33/948; C; C07; C07K; C07K16/00; C07K16/44; Y; Y10; Y10S; Y10S436/00; Y10S436/815; Y10S436/816; Y10S436/823; Y10S530/00; Y10S530/806
Claims Analysis
Total Claims: 0
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References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1976-10-15 | 1977-04-16 | 1977-10-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1980-10-15 | 1981-04-16 | 1981-10-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1984-10-15 | 1985-04-16 | 1985-10-16 | $7700.00 | Window Closed / Lapsed |