US3764604A
Expired / Lapsed
US
⏱️ 0.0 years remaining
4-pyridylcarbinolamine anti-malarials
Assignee: United States Department of the Army
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Filing: 1971-06-07
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Granted: 1973-10-09
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Expires: 1991-06-07
Abstract
Abstract A series of 4-pyridylcarbinolamines is herein disclosed which has value in treatment of plasmodial infections. The compounds have substituted phenyl groups at positions 2- and 6- on the pyridine moiety, with the electronegative substituents (the same, or different) present on the phenyl nuclei. The syntheses of such series is described, together with a method for separation of racemates of a representative 4-pyridyl-carbinolamine type.
Inventors
- 👤 A Ash
- 👤 C Stevens
- 👤 A Markovac
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 23:26
CPC Classifications
C; C07; C07D; C07D213/00; C07D213/02; C07D213/04; C07D213/24; C07D213/28; C07D213/30; C07D213/26; C07D213/44; C07D213/46; C07D213/50; C07D213/60; C07D213/78; C07D213/79
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
26 words
The compound according to claim 1 wherein (Ar)2 and (Ar)6 are the same or different functional groupings which are both halogen-substituted phenyl moieties, and salts thereof.
Claim 2
Dependent Claim
26 words
The compound according to claim 1 wherein (Ar)2and (Ar)6 are the same or different functional groupings which are both chloro-or bromo-substituted phenyl moieties, and salts thereof.
Claim 3
Dependent Claim
19 words
The compound according to claim 3 having (Ar)2 and (Ar)6 both as 4-chloro-phenyl groupings, and salts of said bases.
Claim 4
Dependent Claim
8 words
The compound, 2-4-(-bromophenyl)-6-(4-trifluoromethylphenyl)-2-4(-bromophenyl)-6-(4 -chlorophenyl)-4-chlorophenyl)-4-alpha-(n-butylamine)methylpridine carbinol and salts thereof.
Claim 5
Dependent Claim
7 words
The compound 2,6-bis-(4-Chlorophenyl)-4-alpha-(2-piperidyl)pyridine carbinol and its salts.
Claim 6
Dependent Claim
7 words
The compound 2,6-bis-(4-chlorophenyl)-4-alpha-(2-quinuclidinyl)pyridine carbinol and its salts.
Claim 7
Dependent Claim
3 words
The compound alpha-(di-n-butylaminomethyl)-2,6-bis-(4-fluorophenyl)-4-pyridinecarbinol.
Claim 8
Dependent Claim
3 words
The compound alpha-di-n-butylaminomethyl)-2,6-bis-(4-bromophenyl-4-pyridinecarbinol.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1976-10-08 | 1977-04-09 | 1977-10-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1980-10-08 | 1981-04-09 | 1981-10-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1984-10-08 | 1985-04-09 | 1985-10-09 | $7700.00 | Window Closed / Lapsed |