Is resolution and symmetry control in continuous free flow electrophores
Abstract
Abstract IN A CONTINUOUS FREE FLOW ELECTROPHORESIS APPARATUS HAVING A THIN CURTAIN OF LIQUID CARRIER MEDIUM WHICH FLOWS ALONG THE LENGTH OF AN ELECTROPHORESIS SPACE BETWEEN A PAIR OF SPACED WALLS, THERE IS DISCLOSED A METHOD AND MEANS FOR ADJUSTING THE EFFECTIVE ZETA POTENITAL OF THE WALLS TO OPTIMIZE RESOLUTION AND TO COMPENSATE FOR ASYMMETRY OF THE CELL. RESOLUTION IS OPTIMIZED BY PROVIDING EACH OF THE WALLS OF THE APPARATUS WITH AREAS SPACED ALONG THE LENGTH THEREOF HAVING DIFFERENT ZETA POTENTIALS AND BY EITHER MECHANICALLY OR ELECTRICALLY ADJUSTING THE RELATIVE ELECTROOSMOTIC CONTRIBUTION OF EACH AREA. ASYMMETRY IS ELIMINATED BY MECHANICALLY OF ELECTRICALLY ADJUSTING THE ASYMMETRIES IN THE AREAS OF THE APPARATUS TO BE OPPOSITE IN SENSE TO EACH OTHER.
Inventors
- 👤 A Strickler
Bibliographic Details
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