US3755349A
Expired / Lapsed
US
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Alpha-substituted benzyl-imidazoles
Assignee: Bayer AG
•
Filing: 1971-07-22
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Granted: 1973-08-28
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Expires: 1991-07-22
Abstract
Abstract 1-Benzylimidazoles and 1-benzyl-1,2,4-triazoles bearing both an alkyl, phenyl or cycloalkyl group and a formyl, alkanoyl, aroyl or cycloalkylcarbonyl group on the Alpha -carbon atom of the benzyl group, as well as the ketals, acetals, oximes and semicarbazones thereof, are antimycotic agents. They are prepared by treating the corresponding Alpha -halobenzyl compounds with imidazole or 1,2,4-triazole or the corresponding Alpha hydroxybenzyl compounds with the appropriate thionyl bisazole. A typical embodiment is the preparation of diphenyl-acetylimidazol-1-yl-methane from 1-bromo-1,1-diphenyl-2-propanone and imidazole.
Inventors
- 👤 H Timmler
- 👤 M Plempel
- 👤 W Draber
- 👤 K Buchel
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 10:13
CPC Classifications
C; C07; C07D; C07D231/00; C07D231/02; C07D231/10; C07D231/12; A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/41; A61K31/415; C07D233/00; C07D233/54; C07D233/64; C07D249/00; C07D249/02; C07D249/08
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
48 words
A compound according to claim 1 wherein A is lower alkyl, phenyl, fluorophenyl, chlorophenyl, or methylphenyl; B is hydrogen, lower alkyl or phenyl and X and Y taken independently are lower alkoxy or X and Y taken together are oxygen, or a pharmaceutically acceptable acid addition salt thereof.
Claim 2
Dependent Claim
10 words
The compound according to claim 2 which has the formula:
Claim 3
Dependent Claim
10 words
The compound according to claim 2 which has the formula:
Claim 4
Dependent Claim
10 words
The compound according to claim 2 which has the formula:
Claim 5
Dependent Claim
10 words
The compound according to claim 2 which has the formula:
Claim 6
Dependent Claim
10 words
The compound according to claim 2 which has the formula:
Claim 7
Dependent Claim
10 words
The compound according to claim 2 which has the formula:
Claim 8
Dependent Claim
10 words
The compound according to claim 2 which has the formula:
References Cited (Backward Citations)
US3236856A
Cited
FR1486817A
Cited
US3468902A
Cited
GB1170188A
Cited
US3575999A
Cited
US3658813A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1976-08-27 | 1977-02-26 | 1977-08-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1980-08-27 | 1981-02-26 | 1981-08-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1984-08-27 | 1985-02-26 | 1985-08-28 | $7700.00 | Window Closed / Lapsed |