Piperazine derivatives and processes for their manufacture

Abstract

Abstract C6H5-CO-CH=CH-D WHEREIN D MEANS ON A, OK, O-ALKYL, OH, CL OR BR AND WHEREIN THE BENZENE RING MAY BE SUBSTITUTED AS INDICATED ABOVE WITH A PIPERAZINE COMPOUND OF THE GENERAL FORMULA C6H5-CO-CH=CH- WHEREBY R REPRESENTS AN ALKYL GROUP HAVING FROM 1 TO 4 CARBON ATOMS AND THE BENZENE RINGS B AND/OR C MAY BE SUBSTITUTED BY HALOGEN, AN ALKYL AND/OR ALKOXY GROUP HAVING EACH FROM 1 TO 4 CARBON ATOMS, AND/OR BY A NITRO GROUP AND TO THE PRODUCTION OF SUCH DERIVATIVES BY REACTING A COMPOUND OF THE GENERAL FORMULA 1-A-PIPERAZINE WHEREIN THE BENZENE RING MAY BE SUBSTITUTED AS INDICATED ABOVE WITH PIPERAZINE. C6H5-CO-C*CH WHEREIN A HAS THE MEANING GIVEN ABOVE, OR BY REACTING, AT A MOLAR RATIO OF 2:1, A COMPOUND OF THE GENERAL FORMULA 1-A-PIPERAZINE WHEREIN THE BENZENE RING MAY BE SUBSTITUTED AS INDICATED ABOVE WITH A COMPOUND OF THE GENERAL FORMULA C6H5-CO-C*CH WHEREIN D MEANS ONA, OK, O-ALKYL, OH, CL OR BR AND WHEREIN THE BENZENE RING MAY BE SUBSTITUTED AS INDICATED ABOVE WITH PIPERAZINE, OR BY REACTING A COMPOUND OF THE GENERAL FORMULA C6H5-CO-CH=CH-D WHEREIN A HAS THE MEANING GIVEN ABOVE, OR BY REACTING, AT A MOLAR RATIO OF 2:1, A COMPOUND OF THE GENERAL FORMULA WHEREIN A MEANS AN ALKYL OR HYDROXYALKYL RADICAL HAVING FROM 1 TO 4 CARBON ATOMS IN THE ALKYL MOIETIES, A BENZYHYDRYL OR PHENYL RADICAL OR ONE OF THE GROUPS -COOR OR 1-A,4-(C6H5-CO-CH=CH-)PIPERAZINE THE PRESENT INVENTION RELATES TO NEW, PHARMACOLOGICALLY VALUABLE PIPERAZINE DERIVATIVES OF THE GENERAL FORMULA

Inventors

• 👤 T Raabe
• 👤 K Resag
• 👤 R Nitz

Bibliographic Details