Method and apparatus for determining thyroid function
Abstract
Abstract METHOD AND APPARATUS FOR MEASURING THE TOTAL AMOUNT OF THYROID HORMONE WITHIN A BODY FLUID. THE PROCEDURE INCLUDES AN EXTRACTION STEP WHEREBY THYROID HORMONE (THYROXINE) IS INITIALLY EXTRACTED FROM A BLOOD SAMPLE BY ACIDIFYING THE SAMPLE AND THEREAFTER EXTRACTING THE THYROXINE WITH A SOLVENT SUCH AS ALCOHOL. AN ALIQUOT OF THE SOLVENT CONTAINING THE EXTRACTED THYROXINE IS PLACED INTO A SHALLOW WELL RECEPTACLE AND THE SOLVENT IS THEN EVAPORATED BY AN IMPINGING AIRSTREAM. THE SHALLOW WELL RECEPTACLE IS ADAPTED TO COOPERATE IN SEALING RELATIONSHIP WITH THE OPEN END OF A BUFFER-CONTAINING VIAL SO THAT WHEN IN PLACE, A BUFFER SOLUTION CONTAINING KNOWN AMOUNTS OF THYROBINDING GLOBULIN AND RADIOISOTOPE LABELED THYROID HORMONE CAN BE MIXED WITH THE DRIED THYROXINE BY MERELY INVERTING THE VIAL. D R A W I N G
Inventors
- 👤 A Eisentraut
Bibliographic Details
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